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Modelling Cutaneous Senescence Process

  • Conference paper
Computational Science and Its Applications – ICCSA 2010 (ICCSA 2010)

Abstract

During the last years, skin aging has become an area of increasing research interest. High frequency ultrasound allows the “in vivo” appreciation of certain histological parameters and offers new characteristic markers, which may quantify the severity of the cutaneous senescence process. This paper focuses on measuring the changes in skin thickness and dermis echogenicity , as part of the complex ageing process, on different intervals of age. In particular by using a multiscale approach we will compute some parameters which are connected with complexity (fractal structure) of skin ageing.

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References

  1. Gniadecka, M., Jemec, G.B.E.: Quantitative evaluation of chronological aging and photoageing in vivo: studies on skin echogenicity and thickness. British Journal of Dermatology D92, 138:00-00 (1998)

    Google Scholar 

  2. Monika-Hildegard Schmid-Wendtner, M.D., Walter Burgdorf, M.D.: Ultrasound Scanning in Dermatology. Arch. Dermatol. 141, 217–224 (2005)

    Article  Google Scholar 

  3. Lasagni, C., Seidenari, S.: Echographic assessment of age dependant variations of skin thickness: a study on 162 subjects. Skin. Res. Technol. 1, 81–85 (1995)

    Article  Google Scholar 

  4. Tsukhara, K., Takema, Y., Moriwaki, S., Fujimura, T., Kitahara, T., Immokava, G.: Age related alterations of echogenicity in Japanese skin. Dermatology 200, 303–307 (2000)

    Article  Google Scholar 

  5. Seidenari, S., Pagnoni, A., Dinando, A., Giannetti, A.: Echographic Evaluation with Image Analysis of Normal Skin: Variations according to age and sex. Skin Pharmacol. 7, 201–209 (1994)

    Article  Google Scholar 

  6. Gniadecka, M., Gniadecki, R., Serup, J., Søndergaard, J.: Ultrasound Structure and Digital Image Analysis of the Subepidermal Low Echogenic Band in Aged Human Skin: Diurnal Changes and Interindividual Variability. Journal of Investigative Dermatology 102, 362–365 (1994)

    Article  Google Scholar 

  7. Gniadecka, M.: Effects of aging on dermal echogenicity. Skin Research and Technology 7, 204–207 (2001)

    Article  Google Scholar 

  8. Brancheta, M.C., Boisnicb, S., Francesc, C., Roberta, A.M.: Skin Thickness Changes in Normal Aging Skin. International Journal of Experimental, Clinical Behavioural, Regenerative and Technological Gerontology 36(1), 28–35 (1990)

    Google Scholar 

  9. Pellacani, G., Seidenari, S.: Variations in facial skin thickness and Echogenicity with site and age. Acta Dermatologica Venerologica 79, 366–369 (1999)

    Article  Google Scholar 

  10. Lacarrubba, F., Tedeschi, A., Nardone, B., Micali, G.: Mesotherapy for skin rejuvenation: assessment of the subepidermal low-echogenic band by ultrasound evaluation with cross-sectional B-mode scanning. Dermatologic Therapy 21(3), S1–S5 (2008)

    Article  Google Scholar 

  11. Jemec, G.B.E., Gniadecka, M., Ulrich, J.: Ultrasound in dermatology. Part I. High frequency ultrasound. EJ D. European Journal of Dermatology 10(6), 492–497 (2000)

    Google Scholar 

  12. Szymańska, E., Nowicki, A., Mlosek, K., Litniewski, J., Lewandowski, M., Secomski, W., Tymkiewicz, R.: Skin imaging with high frequency ultrasound — preliminary results. European Journal of Ultrasound 12(1), 9–16 (2000)

    Article  Google Scholar 

  13. Iwamoto, T., Saijo, Y., Hozumi, N., Kobayashi, K., Okada, N., Tanaka, A., Yoshizawa, M.: High frequency ultrasound characterization of artificial skin. In: Conf. Proc. IEEE Eng. Med. Biol. Soc. 2008, pp. 2185–2188 (2008)

    Google Scholar 

  14. Kasper, M., Funk, R.H.W.: Age-related changes in cells and tissues due to advanced glycation end products (AGEs). Archives of Gerontology and Geriatrics 32, 233–243 (2001)

    Article  Google Scholar 

  15. Reiser, K.M.: Nonenzymatic glycation of collagen in aging & diabetes. Proc. Soc. Exp. Biol. Med. 218, 23–37 (1998)

    Google Scholar 

  16. Uitto, J.: The role of elastin and collagen in cutaneous aging: intrinsic aging versus photoexposure. J. DrugsDermatol. 7(Suppl. 2), 12-6 (2008)

    Google Scholar 

  17. Seidenari, S., Giusti, G., Bertoni, L., Magnoni, C., Pellacani, G.: Thickness and echogenicity of the skin in children as assessed by 20-MHZ ultrasound. Dermatology 201, 218–222 (2000)

    Article  Google Scholar 

  18. Fligiel, S.E.G., Varani, J., Datta, S.C., Kang, S., Fisher, G.J., Voorhees, J.J.: Collagen Degradation in Aged/Photodamaged Skin in Vivo and After Exposure to Matrix Metalloproteinase-1 in Vitro. Journal of Investigative Dermatology 120, 842–848 (2003)

    Article  Google Scholar 

  19. Nishimori, Y., Edwards, C., Pearse, A., Matsumoto, K., Kawai, M., Marks, R.: Degenerative Alterations of Dermal Collagen Fiber Bundles in Photodamaged Human Skin and UV-Irradiated Hairless Mouse Skin: Possible Effect on Decreasing Skin Mechanical Properties and Appearance of Wrinkles. Journal of Investigative Dermatology 117, 1458–1463 (2001)

    Google Scholar 

  20. Rexbye, H., Petersen, I., Johansens, M., Klitkou, L., Jeune, B., Christensen, K.: Influence of environmental factors on facial ageing. Age and Ageing 35(2), 110–115 (2006)

    Article  Google Scholar 

  21. Lee, J.Y., Kim, Y.K., Sea, J.Y., Choi, C.W., Hwang, J.S., Lee, B.G., Chang, I.S., Chung, J.H.: Loss of elastic fibers causes skin wrinkles in sun-damaged human skin. Journal of dermatological science 50(2), 99–107 (2008)

    Article  Google Scholar 

  22. Eisenbeiss, C., Welzel, J., Eichler, W., Klotz, K.: Influence of body water distribution on skin thickness: measurements using high-frequency ultrasound. Br. J. Dermatol 144, 947–951 (2001)

    Article  Google Scholar 

  23. Sator, G., Schmidt, J.B., Hönigsmann, H.: objective assessment of photoageing effects using high-frequency ultrasound in PUVA-treated psoriasis patients. British Journal of Dermatology 147(2), 291–298

    Google Scholar 

  24. Diana, C., Calderone, M.D.: The clinical spectrum of actinic elastosis. Journal of the American Academy of Dermatology - 32(6) (June 1995)

    Google Scholar 

  25. Yaar, M., Glichrest, B.A.: Skin aging: postulated mechanisms and consequent changes in structure and function. Clin. Geriart. Med. 17, 617–630 (2001)

    Article  Google Scholar 

  26. Lautenschlager, S., Christian Wulf, H., Pittelkow, M.R.: Photoprotection. The Lancet 370(9586), 528–537 (2007) (Original Text)

    Article  Google Scholar 

  27. Fisher, G.J., Kang, S., Varani, J., et al.: Mechanisms of photoaging and chronological skin aging. Arch. Dermatol. 138, 1462–1470 (2002)

    Article  Google Scholar 

  28. Thomas R. Fears, Joseph Scotto Andmarvin A. Schneiderman; Ultraviolet effects on the incidence of skin cancer among whites in the united states;Field Studies and Statistics Program and the Demography Section, Biometry Branch, National Cancer Institute Bethesda, MD 20014.

    Google Scholar 

  29. Stephen Brown, K., Math, B., Forbes, W.F.: PhD, DSc2; A Mathematical Model of Aging Processes. II1; Dept. of Statistics, Faculty of Mathematics, Univ. of Waterloo Waterloo, Ont. N2L 3G1

    Google Scholar 

  30. DermaScan, C.: Cortex Technology, Denmark, http://www.cortex.dk/dermascan_c.htm

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Crisan, M. et al. (2010). Modelling Cutaneous Senescence Process. In: Taniar, D., Gervasi, O., Murgante, B., Pardede, E., Apduhan, B.O. (eds) Computational Science and Its Applications – ICCSA 2010. ICCSA 2010. Lecture Notes in Computer Science, vol 6017. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12165-4_18

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  • DOI: https://doi.org/10.1007/978-3-642-12165-4_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12164-7

  • Online ISBN: 978-3-642-12165-4

  • eBook Packages: Computer ScienceComputer Science (R0)

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