Abstract
Single measures of breast density have been consistently related to breast cancer risk, but the role of changes in breast density over the early menopausal period is not clear. We investigated determinants and consequences of change in breast density among 493 women in Scotland. Using simple measures of change, only hormone replacement therapy use and current body mass index were consistently predictive of breast density change. Increases in area-based percent breast density were related to higher breast cancer risk, although the analysis was based on very few women. Modeling of change and rate of change in larger datasets is warranted.
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Jeffreys, M., Warren, R., Highnam, R., Davey Smith, G. (2010). Determinants and Consequences of Change in Breast Density. In: MartÃ, J., Oliver, A., Freixenet, J., MartÃ, R. (eds) Digital Mammography. IWDM 2010. Lecture Notes in Computer Science, vol 6136. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13666-5_53
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DOI: https://doi.org/10.1007/978-3-642-13666-5_53
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