Abstract
More and more experimental data indicate that small RNAs play the important role in regulating physiological process. At the same time, the negative feedback loop can induce some interesting phenomena. So we plan to combine the small RNAs with double negative feedback loops, and construct a motif with biological function in this paper.
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Tu, K.C., Christopher, M.W., Svenningsen, S.L., Bassler, B.L.: A Small-RNA-mediated Negative Feedback Loop Controls Quorum-sensing Dynamics in Vibrio Harveyi. Molecular Microbiology 70(4), 896–907 (2008)
Lewis, B.P., Shih, I.H., Jones-Rhoades, M.W., Bartel, D.P., Burge, C.B.: Prediction of Mammalian MicroRNA Targets. Cell 115, 787–798 (2003)
Krek, A., Grun, D., Poy, M.N., Wolf, R., Rosenberg, L., Epstein, E.J., MacMenamin, P., da Piedade, I., Gunsalus, K.C., Stoffel, M., Rajewsky, N.: Combinatorial MicroRNA Target Predictions. Nat. Genet. 37, 495–500 (2005)
Ambros, V.: The functions of Animal MicroRNAs. Nature 431, 350–355 (2004)
Erel, L., Zhongge, Z., Thomas, K.: Terence Hwa. Quantitative Characteristic of Gene Regulation by small RNA. PLoS Biology 5(9), 1998–2010 (2007)
Yisha, S., Gilgi, F., Guy, H., Gali, N., Shoshy, A., Ofer, B., Hanah, M.: Regulation of Gene Expression by Small Non-coding RNAs: a Quantitative View. Molecular Systems Biology 3(138), 1–9 (2007)
Zhong-Ru, X., Hsih-Te, Y., Wei-Chung, L., Ming-Jing, H.: The role of microRNA in the Delayed Negative Feedback Negulation of Gene Expression. Biochemical and Biophysical Research Communications 358, 722–726 (2007)
Shigui, R., Junjie, W.: On the Zeros of a Third Degree Exponential Polynomial with Application to a Delayed Model for the Control of Testosterone Secretion. IMA Journal of Mathematics Applied in Medicine and Biology 18, 41–52 (2001)
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Shen, J., Miao, B., Xu, Y. (2010). Oscillatory Dynamics of Double Negative Feedback Loop Motif by MicroRNAs. In: Huang, DS., McGinnity, M., Heutte, L., Zhang, XP. (eds) Advanced Intelligent Computing Theories and Applications. ICIC 2010. Communications in Computer and Information Science, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14831-6_16
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DOI: https://doi.org/10.1007/978-3-642-14831-6_16
Publisher Name: Springer, Berlin, Heidelberg
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