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Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 6278))

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Abstract

While computation of biological information takes center stage in today’s research, knowledge-based query processing in biological databases has not gained much attention. The complex relationship among biological entities, and the numerous possibilities make it extremely difficult for a user to query data repositories in traditional ways since the information users seek are often not stored directly as extents. Thus, to meaningfully query such repositories, users often write complex applications to compute the needed response based on universal knowledge, or user specific hypothesis. In this paper, we propose a new data model based on object-oriented deductive databases and ontological concepts to allow knowledge-based querying. We propose a new query language called ConLog (for Concept Logic) in the direction of the acclaimed F-Logic and show that ConLog is able to express biological information and support queries in intuitive and user specific ways.

Research supported in part by National Science Foundation grants CNS 0521454 and IIS 0612203.

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References

  1. Bugliesi, M.: A declarative view of inheritance in logic programming. In: JICSLP, pp. 113–127 (1992)

    Google Scholar 

  2. Bugliesi, M., Jamil, H.: A logic for encapsulation in object oriented languages. In: Penjam, J. (ed.) PLILP 1994. LNCS, vol. 844, pp. 215–229. Springer, Heidelberg (1994)

    Google Scholar 

  3. Bugliesi, M., Lamma, E., Mello, P.: Modularity in logic programming. J. Log. Program. 19/20, 443–502 (1994)

    Article  MathSciNet  Google Scholar 

  4. Bunge, M.: Treatise on Basic Philosophy. Ontology I: The Furniture of the World, vol. 3. D. Reidel Publishing Company, Inc., New York (1977)

    Google Scholar 

  5. Bunge, M.: Treatise on Basic Philosophy. Ontology II: A World of Systems, vol. 4. D. Reidel Publishing Company, Inc., New York (1979)

    Google Scholar 

  6. Dey, S., Hossain, S., Jamil, H.: A knowledge-based middleware to support cooperative response to natural language queries over structured scientific databases. Technical report, March 2010. Under review, ACM UIST (2010)

    Google Scholar 

  7. Elhai, J., Taton, A., Massar, J.P., Myers, J.K., Travers, M., Casey, J., Slupesky, M., Shrager, J.: Biobike: A web-based, programmable, integrated biological knowledge base. Nucleic Acids Research 37(Web-Server-Issue), 28–32 (2009)

    Article  Google Scholar 

  8. Gruber, T.R.: A translation approach to portable ontology specifications. Knowledge Acquisition 5, 199–220 (1993)

    Article  Google Scholar 

  9. Horrocks, I.: Scalable ontology-based information systems. In: EDBT, p. 2 (2010)

    Google Scholar 

  10. Horrocks, I., Patel-Schneider, P.F., Bechhofer, S., Tsarkov, D.: Owl rules: A proposal and prototype implementation. J. Web Sem. 3(1), 23–40 (2005)

    Google Scholar 

  11. Hosain, S., Jamil, H.: Empowering OWL with overriding inheritance, conflict resolution and non-monotonic reasoning. In: AAAI Spring Symposium on Social Semantic Web: Where Web 2.0 meets Web 3.0 (2009)

    Google Scholar 

  12. Hosain, S., Jamil, H.: OWL that can choose to inherit and hide it too. In: IEEE International Conference on Semantic Computing, Berkeley, CA (September 2009)

    Google Scholar 

  13. Jamil, H.M.: A logic based language for parametric inheritance. In: Knowledge Representation, Breckenridge, CO, pp. 611–622 (April 2000)

    Google Scholar 

  14. Jamil, H.M., Lakshmanan, L.: A declarative semantics for behavioral inheritance and conflict resolution. In: ILPS (1995)

    Google Scholar 

  15. Kashyap, V., Borgida, A.: Representing the umls semantic network using owl (or ”what’s in a semantic web link?”). In: Fensel, D., Sycara, K., Mylopoulos, J. (eds.) ISWC 2003. LNCS, vol. 2870, pp. 1–16. Springer, Heidelberg (2003)

    Chapter  Google Scholar 

  16. Kifer, M., Lausen, G., Wu, J.: Logical foundations of object-oriented and frame-based languages. Journal of ACM 42(4), 741–843 (1995)

    Article  MATH  MathSciNet  Google Scholar 

  17. Knappe, R., Bulskov, H., Andreasen, T.: Perspectives on ontology-based querying. Int. J. Intell. Syst. 22(7), 739–761 (2007)

    Article  MATH  Google Scholar 

  18. Mabotuwana, T.D.S., Warren, J.: An ontology-based approach to enhance querying capabilities of general practice medicine for better management of hypertension. Artificial Intelligence in Medicine 47(2), 87–103 (2009)

    Article  Google Scholar 

  19. Monteiro, L., Porto, A.: A transformational view of inheritance in logic programming. In: ICLP, pp. 481–494 (1990)

    Google Scholar 

  20. Wolstencroft, K., Brass, A., Horrocks, I., Lord, P.W., Sattler, U., Turi, D., Stevens, R.: A little semantic web goes a long way in biology. In: Gil, Y., Motta, E., Benjamins, V.R., Musen, M.A. (eds.) ISWC 2005. LNCS, vol. 3729, pp. 786–800. Springer, Heidelberg (2005)

    Chapter  Google Scholar 

  21. Yang, G., Kifer, M.: Well-founded optimism: Inheritance in frame-based knowledge bases. In: Meersman, R., Tari, Z., et al. (eds.) CoopIS 2002, DOA 2002, and ODBASE 2002. LNCS, vol. 2519, pp. 1013–1032. Springer, Heidelberg (2002)

    Chapter  Google Scholar 

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Jamil, H. (2010). Talking Biology in Logic, and Back. In: Setchi, R., Jordanov, I., Howlett, R.J., Jain, L.C. (eds) Knowledge-Based and Intelligent Information and Engineering Systems. KES 2010. Lecture Notes in Computer Science(), vol 6278. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15393-8_46

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  • DOI: https://doi.org/10.1007/978-3-642-15393-8_46

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15392-1

  • Online ISBN: 978-3-642-15393-8

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