Abstract
In this work, we investigate a new method to search DNA sequences based on multimedia retrieval approach. We try to address the issues related to index sizes and performance by first transforming the DNA sequences into images, and then index these images using content-based image indexing techniques. The main goal is to allow users retrieve similar gene sequences using stored image features rather than the sequence itself. We suggest two algorithms to do the conversions, each of which have been tested to reveal its sensitivity to both sequence length and sequence changes. We have also compared our approach to BLAST, which were used as a reference system. The result from our experiments has shown that this approach performed well with respect to size and speed, but more work must be done to improve it in terms of search sensitivity.
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Ramampiaro, H., Grande, A. (2011). DNA Sequence Search Using Content-Based Image Search Approach. In: Rocha, M.P., RodrÃguez, J.M.C., Fdez-Riverola, F., Valencia, A. (eds) 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Advances in Intelligent and Soft Computing, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19914-1_26
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DOI: https://doi.org/10.1007/978-3-642-19914-1_26
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