Abstract
Medial temporal lobe (MTL) is a region of the brain related with processing and declarative memory consolidation. Structural changes in this region are directly related with Alzheimer’s disease and other dementias. Manual delimitation of these structures is very time consuming and error prone. Automatic methods are needed in order to solve these problems and make it available in the clinical practice. Unfortunately, automatic methods are not robust enough yet. The use of semiautomatic methods provides an intermediate solution with the advantages of automatic methods under the supervision of the expert. This paper propose two semiautomatic methods oriented to make the delineation of the MTL structures easy, robust and fast.
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References
Dale, A.M., Fischl, B., Sereno, M.I.: Cortical surface-based analysis I: Segmentation and surface reconstruction. Neuroimage 9, 179–194 (1999)
Fischl, B., Kouwe, A., Destrieux, C., Halgren, E., Segonne, F., Salat, D.H., Busa, E., Seidman, L.J., Goldstein, J., Kennedy, D., Caviness, V., Makris, N., Rosen, B., Dale, A.M.: Automatically Parcellating the Human Cerebral Cortex. Cerebral Cortex 14, 11–22 (2004)
Ibáñez, L., Schroeder, W., Ng, L., Cates, J., Consortium, T.I.S., Hamming, R.: The ITK Software Guide. Kitware, Inc. (January 2003)
Insausti, R., Juottonen, K., Soininen, H., Insausti, A., Partanen, K., Vainio, P., Laakso, M.P., Pitkanen, A. M.: VolumetricAnalysis of the Human Entorhinal, Perirhinal, and Temporopolar Cortices. AJNR Am. J. Neuroradiol. 19, 656–671 (1998)
Insausti, R., Insausti, A.M., Mansilla, F., Abizanda, P., Artacho-Pérula, E., Arroyo-Jimenez, M.M., Martinez-Marcos, A., Marcos, P.: The human parahippocampal gyrus. In: 3th Annual Meeting of Society for Neuroscience Anatomical and MRI correlates, New Orleans, USA (November 2003)
Insausti, R., Rincón, M., González-Moreno, C., Artacho-Pérula, E., Díez-Peña, A., García-Saiz, T.: Neurobiological significance of automatic segmentation: Application to the early diagnosis of alzheimer’s disease. In: Mira, J., Ferrández, J.M., Álvarez, J.R., de la Paz, F., Toledo, F.J. (eds.) IWINAC 2009. LNCS, vol. 5602, pp. 134–141. Springer, Heidelberg (2009)
Juottonen, K., Laakso, M.P., Insausti, R., Lehtovirta, M., Pitkanen, A., Partanen, K., Soininen, H.: Volumes of the Entorhinal and Perirhinal Cortices in Alzheimer’sDisease. Neurobiology of Aging 19 (1998)
Klauschen, F., Goldman, A., Barra, V., Meyer-Lindenberg, A., Lundervold, A.: Evaluation of Automated Brain MR Image Segmentation and Volumetry Methods. Human Brain Mapping 30, 1310–1327 (2009)
Hu, Y.J., Grossberg, M.D., Mageras, G.S.: Semiautomatic medical image segmentation with adaptive local statistics in conditional random fields framework. In: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 3099–3102 (2008)
Nowinski, et al.: A New Presentation and Exploration of Human Cerebral Vasculature Correlated With Surface and Sectional. Neuroanatomy Anat. Sci. Ed. 2, 24–33 (2009)
Pichon, E., Tannenbaum, A., Kikinis, R.: A statistically based flow for image segmentation. Med. Image Anal. 8(3), 267–274 (2004)
Pieper, S., Lorensen, B., Schroeder, W., Kikinis, R.: The NA-MIC Kit: ITK, VTK, Pipelines, Grids and 3D Slicer as an Open Platform for the Medical Image Computing Community. In: Proceedings of the 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro 2006, vol. 1, pp. 698–701 (2006)
Sánchez-Benavidesab, G., Gómez-Ansónc, B., Sainzd, A., Vivesd, Y., Delfinod, M., Peña-Casanova, J.: Manual validation of FreeSurfer’s automated hippocampal segmentation in normal aging, mild cognitive impairment. Alzheimer Disease subjects 181(3), 219–225 (2010)
Scoville, W.B., Milner, B.: Loss of recent memory after bilateral hippocampal lesions. J. Neurol. Neurosurg. Psychiatry 20, 11–21 (1957)
Squire, L.R., Stark, C., Clark, R.E.: The medial temporal lobe. Annu. Rev. Neurosci. 27, 279–306 (2004)
Smith, S.M., Jenkinson, M., Woolrich, M.W., Beckmann, C.F., Behrens, T.E.J., Johansen- Berg, H., Bannister, P.R., De Luca, M., Drobnjak, I., Flitney, D.E., Niazy, R., Saunders, J., Vickers, J., Zhang, Y., De Stefano, N., Brady, J.M., Matthews, P.M.: Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23, 208–219 (2004)
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Rincón, M. et al. (2011). Semiautomatic Segmentation of the Medial Temporal Lobe Anatomical Structures. In: Ferrández, J.M., Álvarez Sánchez, J.R., de la Paz, F., Toledo, F.J. (eds) New Challenges on Bioinspired Applications. IWINAC 2011. Lecture Notes in Computer Science, vol 6687. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21326-7_4
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DOI: https://doi.org/10.1007/978-3-642-21326-7_4
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