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Automated Detection of Junctions Structures and Tracking of Their Trajectories in 4D Images

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Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 6801))

Abstract

Junction structures, as the natural anatomical markers, are useful to study the organ or tumor motion. However, detection and tracking of the junctions in four-dimensional (4D) images are challenging. The paper presents a novel framework to automate this task. Detection of their centers and sizes is first achieved by an analysis of local shape profiles on one segmented reference image. Junctions are then separately tracked by simultaneously using neighboring intensity features from all images. Defined by a closed B-spline space curve, the individual trajectory is assumed to be cyclic and obtained by maximizing the metric of combined correlation coefficients. Local extrema are suppressed by improving the initial conditions using random walks from pair-wise optimizations. Our approach has been applied to analyze the vessel junctions in five real 4D respiration-gated computed tomography (CT) image datasets with promising results. More than 500 junctions in the lung are detected with an average accuracy of greater than 85% and the mean error between the automated and the manual tracking is sub-voxel.

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References

  1. Palagyi, K., Tschirren, J., Hoffman, E.A., Sonka, M.: Quantitative Analysis of Pulmonary Airway Tree Structures. Comput. Biol. Med. 36(9), 974–996 (2006)

    Article  Google Scholar 

  2. Castillo, R., Castillo, E., Guerra, R., Johnson, V.E., McPhail, T., Garg, A.K., Guerrero, T.: A Framework for Evaluation of Deformable Image Registration Spatial Accuracy Using Large Landmark Point Sets. Phys. Med. Biol. 54(7), 1849–1870 (2009)

    Article  Google Scholar 

  3. Murphy, K., van Ginneken, B., Klein, S., Staring, M., de Hoop, B.J., Viergever, M.A., Pluim, J.P.: Semi-Automatic Construction of Reference Standards for Evaluation of Image Registration. Med. Image Anal. 15(1), 71–84 (2011)

    Article  Google Scholar 

  4. Boldea, V., Sharp, G.C., Jiang, S.B., Sarrut, D.: 4D-CT Lung Motion Estimation with Deformable Registration: Quantification of Motion Nonlinearity and Hysteresis. Med. Phys. 35(3), 1008–1018 (2008)

    Article  Google Scholar 

  5. Metz, C.T., Klein, S., Schaap, M., van Walsum, T., Niessen, W.J.: Nonrigid Registration of Dynamic Medical Imaging Data Using Nd Plus T B-Splines and a Groupwise Optimization Approach. Med. Image Anal. 15(2), 238–249 (2011)

    Article  Google Scholar 

  6. Tashiro, M., Minohara, S., Kanai, T., Yusa, K., Sakurai, H., Nakano, T.: Three-Dimensional Velocity Mapping of Lung Motion Using Vessel Bifurcation Pattern Match-ing. Med. Phys. 33(6), 1747–1757 (2006)

    Article  Google Scholar 

  7. Smeets, D., Bruyninckx, P., Keustermans, J., Vandermeulen, D., Suetens, P.: Robust Matching of 3D Lung Vessel Trees. In: The Third International Workshop on Pulmonary Image Analysis, Beijing, China, pp. 61–70 (2010)

    Google Scholar 

  8. Castillo, E., Castillo, R., Martinez, J., Shenoy, M., Guerrero, T.: Four-Dimensional Deformable Image Registration Using Trajectory Modeling. Phys. Med. Biol. 55(1), 305–327 (2010)

    Article  Google Scholar 

  9. Sluimer, I., Schilham, A., Prokop, M., van Ginneken, B.: Computer Analysis of Computed Tomography Scans of the Lung: A Survey. IEEE T. Med. Imaging 25(4), 385–405 (2006)

    Article  Google Scholar 

  10. Maurer, C.R., Qi, R.S., Raghavan, V.: A Linear Time Algorithm for Computing Exact Euclidean Distance Transforms of Binary Images in Arbitrary Dimensions. IEEE T. Pattern Anal. 25(2), 265–270 (2003)

    Article  Google Scholar 

  11. Sethian, J.A.: Level Set Methods and Fast Marching Methods. Cambridge University Press, Cambridge (1999)

    MATH  Google Scholar 

  12. Comaniciu, D., Meer, P.: Mean Shift: A Robust Approach toward Feature Space Analysis. IEEE T. Pattern Anal. 24(5), 603–619 (2002)

    Article  Google Scholar 

  13. De Boor, C.: A Practical Guide to Splines. Springer, New York (2000)

    MATH  Google Scholar 

  14. Nocedal, J.: Updating Quasi-Newton Matrices with Limited Storage. Math. Comput. 35(151), 773–782 (1980)

    Article  MathSciNet  MATH  Google Scholar 

  15. Byrd, R.H., Lu, P.H., Nocedal, J., Zhu, C.Y.: A Limited Memory Algorithm for Bound Constrained Optimization. SIAM J. Sci. Comput. 16(5), 1190–1208 (1995)

    Article  MathSciNet  MATH  Google Scholar 

  16. Hu, S.Y., Hoffman, E.A., Reinhardt, J.M.: Automatic Lung Segmentation for Accurate Quantitation of Volumetric X-Ray CT Images. IEEE T. Med. Imaging 20(6), 490–498 (2001)

    Article  Google Scholar 

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© 2011 Springer-Verlag Berlin Heidelberg

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Xiong, G., Xing, L. (2011). Automated Detection of Junctions Structures and Tracking of Their Trajectories in 4D Images. In: Székely, G., Hahn, H.K. (eds) Information Processing in Medical Imaging. IPMI 2011. Lecture Notes in Computer Science, vol 6801. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22092-0_40

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  • DOI: https://doi.org/10.1007/978-3-642-22092-0_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-22091-3

  • Online ISBN: 978-3-642-22092-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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