Abstract
Systems for re-annotations of DNA microarray data for supporting analysis of results of DNA microarray experiments are becoming important elements of bioinformatics aspects of gene expression based studies [10]. However, due to the computational problems related to the whole genome browsing projects, available services and data for re-annotation of microarray probes are still quite sparse. The difficulty in developing systems of re-annotations of microarray probe sets is mainly in huge sizes of probe set data.
In our research we have created an efficient re-annotation method by combining the well known gene search tool BLAT with appropriately designed database. The elaborated system extends possibilities of existing re-annotation tools in the sense that: (1) by tuning parameters of all steps of re-annotation procedure any Affymetrix microarray standard chip can be automatically re-annotated in few hours, (2) several Affymetrix microarray chip standards are already precomputed.
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Foszner, P., Gruca, A., Polanski, A., Marczyk, M., Jaksik, R., Polanska, J. (2011). Efficient Algorithm for Microarray Probes Re-annotation. In: Jędrzejowicz, P., Nguyen, N.T., Hoang, K. (eds) Computational Collective Intelligence. Technologies and Applications. ICCCI 2011. Lecture Notes in Computer Science(), vol 6923. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23938-0_29
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DOI: https://doi.org/10.1007/978-3-642-23938-0_29
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