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A Morphological Atlas of Prostate’s Zonal Anatomy for Construction of Realistic Digital and Physical Phantoms

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Book cover Prostate Cancer Imaging. Image Analysis and Image-Guided Interventions (Prostate Cancer Imaging 2011)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 6963))

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Abstract

Validation of computer-aided detection and intervention procedures for prostate cancer is still a challenging issue. Despite the increasing accuracy of prostate image analysis tools, in vivo and in silico validations are necessary before they can be deployed in clinical routine. In this study, we developed a statistical atlas of prostate morphology for construction of realistic digital and physical phantoms. We have been interested in modeling the gland’s zonal anatomy as defined by the peripheral zone and the central gland. Magnetic Resonance Imaging studies from 30 patients were used. Mean shape and most relevant deformations for prostate structures were computed using principal component analysis. The resulting statistical atlas has been used in image simulation and the design of a physical phantom of the prostate.

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© 2011 Springer-Verlag Berlin Heidelberg

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Makni, N., Iancu, A., Puech, P., Mordon, S., Betrouni, N. (2011). A Morphological Atlas of Prostate’s Zonal Anatomy for Construction of Realistic Digital and Physical Phantoms. In: Madabhushi, A., Dowling, J., Huisman, H., Barratt, D. (eds) Prostate Cancer Imaging. Image Analysis and Image-Guided Interventions. Prostate Cancer Imaging 2011. Lecture Notes in Computer Science, vol 6963. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23944-1_3

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  • DOI: https://doi.org/10.1007/978-3-642-23944-1_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-23943-4

  • Online ISBN: 978-3-642-23944-1

  • eBook Packages: Computer ScienceComputer Science (R0)

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