Abstract
The exponential increment in the production of biomedical data is forcing a higher level of automatization to analyze it. Therefore, biomedical researchers have to entrust bioinformaticians to develop software able to process a huge amount of data on high performance unix-based servers. However, most of the software is developed with a very basic, text-based, user interface, usually because of a lack of time. In addition the applications are developed as independent tools yielding to a set of specific software tools with very different ways of use. This implies that final users continuously need developer support. Even worse, in many situations only developers themselves are able to run the software every time is required. In this contribution we present a Web-based user interface that homogenizes the way users interact with the applications installed in a server. This way, authorized users can add their applications to the Web site at a very low cost. Therefore, researchers with no special computational skills will perform analysis by themselves, gaining independence to run applications whenever they want at the cost of a very little effort. The application is portable to any unix-like system with a php+mysql server.
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Abad-Grau, M.M., Medina-Medina, N., Montes-Soldado, R., Moreno-Ortega, J., Matesanz, F.: Genome-wide association filtering using a highly locus-specific transmission/disequilibrium test. Human Genetics 128(3), 325–344 (2010)
Alekseev, O.M., Richardson, R.T., Alekseev, O., O’Rand, M.G.: Analysis of gene expression profiles in hela cells in response to overexpression or sirna-mediated depletion of nasp. Reprod. Biol. Endocrinol. 7, 7–45 (2009)
Blanchet, C., Combet, C., Daric, V., Deléage, G.: Web Services Interface to Run Protein Sequence Tools on Grid, Testcase of Protein Sequence Alignment. In: Maglaveras, N., Chouvarda, I., Koutkias, V., Brause, R. (eds.) ISBMDA 2006. LNCS (LNBI), vol. 4345, pp. 240–249. Springer, Heidelberg (2006)
Dimas, A.S., Deutsch, S., Stranger, B.E., Montgomery, S.B., Borel, C., Attar-Cohen, H., Ingle, C., Beazley, C., Arcelus, M.G., Sekowska, M., Gagnebin, M., Nisbett, J., Deloukas, P., Dermitzakis, E., Antonarakis, S.E.: Common regulatory variation impacts gene expression in a cell type dependent manner. Science 325(5945), 1246–1250 (2001)
Fox, J.A., McMillan, S., Ouellete, B.F.: A compilation of molecular biology web servers: 2006 update on the bioinformatics links directory. Nucleic Acids Research 34, W3–W5 (2001)
Scheet, P., Stephens, M.: A fast and flexible statistical model for large-scale population genotype. data: Applications to inferring missing genotypes and haplotypic phase. Am. J. Hum. Genet. 78, 629–644 (2006)
Sebastiani, P., Abad-Grau, M.M.: Bayesian estimates of linkage disequilibrium. BMC Genetics 8, 1–13 (2007)
Sebastiani, P., Abad-Grau, M.M., Alpargu, G., Ramoni, M.F.: Robust Transmission Disequilibrium Test for incomplete family genotypes. Genetics 168, 2329–2337 (2004)
Slottow, J., Korambath, P., Jin, K.: The integration of ajax, interactive x windows applications and application input generation into the ucla grid portal. In: Proceedings of the IEEE International Symposium on Parallel and Distributed Processing (2008)
Stephens, M., Smith, N.J., Donelly, P.: A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978–989 (2001)
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Grasso, L., Medina-Medina, N., Montes-Soldado, R., Abad-Grau, M.M. (2012). Homogenizing Access to Highly Time-Consuming Biomedical Applications through a Web-Based Interface. In: Alexander, M., et al. Euro-Par 2011: Parallel Processing Workshops. Euro-Par 2011. Lecture Notes in Computer Science, vol 7156. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29740-3_5
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DOI: https://doi.org/10.1007/978-3-642-29740-3_5
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