Abstract
SimTandem is a tool for fast identification of protein and peptide sequences from tandem mass spectra. The identification is based on similarity search of spectra captured by a tandem mass spectrometer in databases of theoretical mass spectra generated from databases of known protein sequences. Since the number of protein sequences in the databases grows rapidly and a sequential scan over the entire database of spectra is time-consuming, the non-metric access methods are employed as the database indexing techniques. SimTandem is based on a previously proposed method and is freely available at http://www.simtandem.org or http://www.siret.cz/simtandem .
This work was supported by Czech Science Foundation (GAČR) projects 202/11/0968, 201/09/H057, by the Grant Agency of Charles University (GAUK) project Nr. 430711 and by the grant SVV-2012-265312.
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References
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Novák, J., Galgonek, J., Hoksza, D., Skopal, T. (2012). SimTandem: Similarity Search in Tandem Mass Spectra. In: Navarro, G., Pestov, V. (eds) Similarity Search and Applications. SISAP 2012. Lecture Notes in Computer Science, vol 7404. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-32153-5_18
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DOI: https://doi.org/10.1007/978-3-642-32153-5_18
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