Abstract
Many cardiovascular diseases are linked to anomalies in myocardial fibers. The purpose of this paper is to model the birefringence of myocardial fibers in polarized light imaging (PLI) with future application to measurements on real myocardial tissues. The method consists in modeling the behavior of a uni-axial birefringent crystal by means of the Muller matrix, and measuring the final intensity of polarized light and consequently the orientation of myocardial fibers, by using crossed polarizers. The method was illustrated with a tissue modeled as a volume of 100×100×500μm3. This volume was divided into cubes of size 20μm close to cell diameter. The fiber orientation within the cube was defined by azimuth and elevation angles. The results showed that the proposed modeling enables us to find the optimal conditions for the PLI of 3D fiber orientations and design a model for the myocardial tissue measurement from PLI.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Mall, F.P.: On the muscular architecture of the ventricles of the human heart. Am. J. Anat. 11, 211–266 (1911)
Robb, J.S., Robb, R.C.: The normal heart-anatomy and physiology of the structural units. Am. Heart J. 23, 455–467 (1942)
Torrent-Guasp, F.: Organizacion de la musculeta cardiaca ventricular. In: Zarco, P., Perez, J. (eds.) El Mecanico del Corazon, pp. 3–36. Ediciones toray, Barcelona (1975)
Hort, W.: Quantitative morphology and structural dynamics of the myocadium. Methods Achiev. Exp. Pathol. 5, 3–21 (1971)
Streeter Jr., D.D.: Gross morphology and fiber geometric of the heart. The Cardiovascular (1979)
Basser, P., Pierpaoli, C.: Microstructural and Physiological Features of Tissues Elucidated by Quantitative-diffusion-tensor MRI. J. Magn. Reson. Imaging 111(3), 209–219 (1996)
Wu, M.T., Tseng, W.Y., Su, M.Y., et al.: Diffusion Tensor Magnetic Resonance Imaging Mapping the Fiber Architecture Remodeling in Human Myocardium After Infarction. Circulation 114(10), 1036–1045 (2006)
Frindel, C., Robini, M., Schaerer, J., Croisille, P., Zhu, Y.M.: A graph-based approach for automatic cardiac tractography. MRM 64, 1215–1229 (2010)
Scmid, P., Jaermann, T., Boesiger, P., Niederer, P.F., Lunkenheimer, P.P., Cryer, C.W., Anderson, R.H.: Ventricular myocardial architecture as visualized in postmortem swine hearts using magnetic resonance diffusion tensor imaging. Eur. J. Cardiothorac. Surg. 27, 468–472 (2005)
Bickel, W.S., Davidson, J.F., Huffman, D.R., Kilkson, R.: Application of polarization effects in light scattering: a new biophysical tool. Proc. Natl. Acad. Sci. USA 73, 486–490 (1976)
Jacques, S.L., Roman, J.R., Lee, K.: Imaging Superficial Tissues With Polarized Light (2000)
Whittaker, P., Boughner, D.R., Kloner, R.A.: Analysis of Healing After Myocardial Infarction Using Polarized Light Microscopy (1989)
Jouk, P.-S., Usson, Y., Michalowicz, G., Grossi, L.: Three dimensional cartography of the pattern of the myofibres in the second trimester fetal human heart. Anat. Embriol. 202, 103–118 (2000)
Jouk, P.-S., Mourad, A., Misilic, V., Michalowicz, G., Raoul, A., Caillerie, D., Usson, Y.: Analysis of the fiber architecture of the heart by quantitative polarized light microscopy, accurancy, limitations and contribution to the study of the fiber architecture of the ventricles during fetal and neonatal life. Journal of Cardio-thoracic Sugery, 916–922 (2007)
Rieppo, J., Hallikainen, J., Jurverlin, J.S., Kiviranta, I., Helminen, H.J., Hyttinen, M.M.: Practical considerations in use of polarized light microscopy in the analysis of the collage Network in cartilage. Microscopy Research and Technique 71, 279–287 (2008)
Jouk, P.-S., Brugal, G.: Etude de la topographie des cellules myocardiques au cours du développement embryonnaire et fœtal (1994)
Wood, M.F.G., et al.: Polarization birefringence measurement for characterizing the myocardium, including healthy, infarcted, and stem-cell-regeneration tissues (2010)
Usson, Y., Parazza, F., Jouk, P.-S., Michalowicz: Method for the study of the three dimensional orientation of the nuclei of myocardial cells in fetal human heart by means confocal scanning laser microscopy. Journal of Microscopy 174(pt. 2), 101–110 (1994)
Walter, et al.: Polarized light microscopy
Brehat, F., Wyncke, B.: Répresentation des états de polarisation des ondes lumineuses (2003)
Methods for mapping of the orientation of myocardial cells by means of polarized light. Assessment by confocal scanning laser microscopy
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Desrosiers, P.A., Michalowicz, G., Jouk, PS., Usson, Y., Zhu, Y. (2013). Modeling of the Optical Behavior of Myocardial Fibers in Polarized Light Imaging. In: Camara, O., Mansi, T., Pop, M., Rhode, K., Sermesant, M., Young, A. (eds) Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. STACOM 2012. Lecture Notes in Computer Science, vol 7746. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36961-2_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-36961-2_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-36960-5
Online ISBN: 978-3-642-36961-2
eBook Packages: Computer ScienceComputer Science (R0)