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A Preliminary Study of Memory Functions in Unaffected First-Degree Relatives of Schizophrenia

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Book cover Intelligent Computing Theories and Technology (ICIC 2013)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 7996))

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Abstract

Schizophrenia is a neuropsychiatric disorder with etiologies caused by both genetic and environmental factors. However, very few studies have been done to examine the differential pattern of working memory dysfunction in individuals at risk for schizophrenia. The current study aimed to examine the different modalities of working memory performances in the first-degree relatives of patients with schizophrenia. Results showed that unaffected first-degree relatives characterized by high but not low schizotypal traits demonstrated significantly poorer performances in the verbal 2-back tasks, the immediate and delayed recall of logical memory compared to healthy controls. These preliminary findings suggest memory function impairment was more closely associated with schizotypal traits in unaffected first-degree relatives of schizophrenia patients.

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Author information

Authors and Affiliations

  1. Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China

    Xiao-Yan Cao, Zhi Li & Raymond C. K. Chan

  2. University of Chinese Academy of Sciences, Beijing, China

    Xiao-Yan Cao

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  1. Xiao-Yan Cao
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  2. Zhi Li
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  3. Raymond C. K. Chan
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Editors and Affiliations

  1. Machine Learning and Systems Biology Laboratory, Tongji University, 4800 Caoan Road, 201804, Shanghai, China

    De-Shuang Huang

  2. School of Electrical Engineering, University of Ulsan, 680-749 #7-413, San 29, Muger Dong, Ulsan, South Korea

    Kang-Hyun Jo

  3. Guangxi University for Nationalities, 530006, Nanning, Guangxi, China

    Yong-Quan Zhou

  4. School of Computer Science and Engineering, Inha University, 402-751, Incheon, South Korea

    Kyungsook Han

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Cao, XY., Li, Z., Chan, R.C.K. (2013). A Preliminary Study of Memory Functions in Unaffected First-Degree Relatives of Schizophrenia. In: Huang, DS., Jo, KH., Zhou, YQ., Han, K. (eds) Intelligent Computing Theories and Technology. ICIC 2013. Lecture Notes in Computer Science(), vol 7996. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39482-9_2

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  • DOI: https://doi.org/10.1007/978-3-642-39482-9_2

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