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Multi-Agent-Based Simulation of Mycobacterium Tuberculosis Growth

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Multi-Agent-Based Simulation XIV (MABS 2013)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 8235))

Abstract

Tuberculosis is an infectious disease that still causes many deaths around the world nowadays. It is caused by the M. tuberculosis bacillus. The study of the growth curve of this infectious organism is relevant as it has wide applications in tuberculosis research. In this work a Multi-Agent-Based Simulation is proposed to pursue the reproduction in silico of the observed in vitro M. tuberculosis growth curves. Simulation results are qualitatively compared with growth curves obtained in vitro with a recent proposed methodology. The results are promising and indicate that the chosen simulation methodology has the potential to serve as a platform for testing different bacterial growing behaviour as well as bacteria growth under different conditions.

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Authors and Affiliations

  1. Grupo de Pesquisa em Biologia Computacional - Centro de Ciências Computacionais, Núcleo de Pesquisa em Microbiologia Médica - Faculdade de Medicina, Universidade Federal do Rio Grande, Rio Grande, Brazil

    Pablo Werlang, Michel Q. Fagundes, Diana F. Adamatti, Karina S. Machado, Andrea von Groll, Pedro E. A. da Silva & Adriano V. Werhli

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  1. Pablo Werlang
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  2. Michel Q. Fagundes
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  3. Diana F. Adamatti
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  4. Karina S. Machado
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  5. Andrea von Groll
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  6. Pedro E. A. da Silva
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  7. Adriano V. Werhli
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Corresponding author

Correspondence to Adriano V. Werhli .

Editor information

Editors and Affiliations

  1. School of Geosciences, University of Edinburgh, Edinburgh, United Kingdom

    Shah Jamal Alam

  2. Soar Technology, Ann Arbor, Michigan, USA

    H. Van Dyke Parunak

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Werlang, P. et al. (2014). Multi-Agent-Based Simulation of Mycobacterium Tuberculosis Growth. In: Alam, S., Parunak, H. (eds) Multi-Agent-Based Simulation XIV. MABS 2013. Lecture Notes in Computer Science(), vol 8235. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54783-6_9

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  • DOI: https://doi.org/10.1007/978-3-642-54783-6_9

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54782-9

  • Online ISBN: 978-3-642-54783-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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