Abstract
A prolonged phase of increased pressure in the upper esophageal sphincter (UES) after swallowing might result in globus sensation. Therefore, it is important to evaluate restitution times of the UES in order to distinguish physiologic from impaired swallow associated activities. Estimating the event \(t^{\star }\) where the UES has returned to its resting pressure after swallowing can be accomplished by predicting if swallowing activities are present or not. While the problem, whether a certain swallow is pathologic or not, is approached in Mielens (J Speech Lang Hear Res 55:892–902, 2012), the analysis conducted in this paper advances the understanding of normal pharyngoesophageal activities.
From the machine learning perspective, the problem is treated as binary sequence labeling, aiming to find a sample \(t^{\star }\) within the sequence obeying a certain characteristic: We strive for a best approximation of label transition which can be understood as a dissection of the sequence into individual parts. Whereas common models for sequence labeling are based on graphical models (Nguyen and Guo, Proceedings of the 24th International Conference on Machine Learning. ACM, New York, pp. 681–688, 2007), we approach the problem using a logistic regression as classifier, integrate sequential features by means of FFT-coefficients and a Laplacian regularizer in order to encourage a smooth classification due to the monotonicity of target labels.
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Altun, Y., Tsochantaridis, I., & Hoffmann, T. (2003). Hidden Markov support vector machines. International Conference on Machine Learning, 3, 3–10.
Collins, M. (2002). Discriminative training methods for hidden markov models: Theory and experiments with perceptron algorithms. In EMNLP (Vol. 10, pp. 1–8).
Fox, M. R., & Bredenoord, A. J. (2008). Oesophageal high-resolution manometry: Moving from research into clinical practice. Gut, 75, 405–423.
Joachims, T., Finley, T., & Chun-Nam, Y. (2009). Cutting-plane training of structured SVMs. Machine Learning Journal, 72(1), 27–59.
Jungheim, M., Miller, S., & Ptok, M. (2013). Methodologische Aspekte zur Hochauflösungsmanometrie des Pharynx und des oberen Ösophagussphinkters. Laryngo-Rhino-Otol, 92, 158–164.
Lafferty, J., McCallum, A., & Pereira, F. (2001). Conditional random fields: Probabilistic models for segmenting and labeling sequence data. In International Conference on Machine Learning (pp. 282–289).
Meyer, S., Jungheim, M., & Ptok, M. (2012). High-resolution manometry of the upper esophageal sphincter. HNO, 60(4), 318–326.
Mielens, J. D., Hoffman, M. R., Ciucci, M. R., McCulloch, T. M., & Jiang, J. J. (2012). Application of classification models to pharyngeal high-resultion manometry. Journal of Speech, Language, and Hearing Research, 55, 892–902.
Nguyen, N., & Guo, Y. (2007). Comparison of sequence labeling algorithms and extensions. In Z. Ghahramani (Ed.), Proceedings of the 24th International Conference on Machine Learning (pp. 681–688). New York, NY: ACM.
Rabiner, L. R. (1989). A tutorial on hidden markov models and selected applications in speech recognition. Proceedings of the IEEE, 77(2), 257–286.
Tashar, B., Guestrin, C., & Koller, D. (2003). Max-margin Markov networks. In Advances in Neural Information Processing Systems (Vol. 16).
Tsochantaridis, I., Joachims, T., Hofmann, T., & Altun, Y. (2005). Large margin methods for structured and interdependent output variables. Journal of Machine Learning Research, 6, 1453–1484.
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Schilling, N., Busche, A., Miller, S., Jungheim, M., Ptok, M., Schmidt-Thieme, L. (2015). Event Prediction in Pharyngeal High-Resolution Manometry. In: Lausen, B., Krolak-Schwerdt, S., Böhmer, M. (eds) Data Science, Learning by Latent Structures, and Knowledge Discovery. Studies in Classification, Data Analysis, and Knowledge Organization. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44983-7_30
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DOI: https://doi.org/10.1007/978-3-662-44983-7_30
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