Abstract
A preliminary study is presented on the potential role of similarity mapping (SM) in the evaluation of oncological dynamic18F-fluorodeoxyglucose positron emission tomography studies, mainly in lesion localisation and detectability. Similarity maps were calculated using previously described (correlation coefficient (COR) and normalised correlation coefficient (NCOR) and newly introduced similarity measures (sum of squares coefficient (SSQ), squared sum coefficient (SQS), sum of cubes coefficient (SC) and cubed sum coefficient (CS)). The results were evaluated using simulated and clinical data. The study revealed that the best-suited similarity measure for such applications was the CS similarity coefficient, which provided the best parametric images, delineating structures of interest and supporting the visual interpretation of data sets. It was shown that SM and standardised uptake value (SUV) images had comparable diagnostic performance, although SM was able to offer additional time-related information in a single image. For the case of colorectal recurrences (17 cases), the measured contrast values for the CS and SUV images were 2.36±0.47 and 4.12±0.42, respectively, whereas, for three cases of giant cell tumours, these values were 11.6±2.1 and 11.9±1.8, respectively.
Similar content being viewed by others
References
Adam, L. E., Zaers, J., Ostertag, J. H., Trojan, H., Bellemann, M. E., andBrix, G. (1997): ‘Performance evaluation of the whole-body PET scanner ECAT EXACT HR/sup +/following the IEC standard’,IEEE Trans. Nucl. Sci.,44, pp. 1172–1179
Alavi, A., andReivich, M. (2002): ‘Guest editorial: the conception of FDG-PET imaging’,Semin. Nucl. Med.,32, pp. 2–5
Amaral, T. G., Crisostomo, M. m., andde Almeida, A. T. (1998): ‘Fuzzy segmentation-an important tool in image processing’.Proc. IEEE World Congress on Computational Intelligence,2, pp. 1577–1582
Bandettini, P. A., Jesmanowicz, A., Wong, E. C., andHyde, J. S. (1993): ‘Processing strategies for time-course data sets in functional MRI of the human brain’,MRM,30, pp. 161–173
Barnea, D. I., andSilverman, H. F. (1972): ‘A class of algorithms for the fast digital image registration’,IEEE Trans. Comput.,21, pp. 179–186
Boudraa, A.-O., Champier, J., Djebali, M., Behloul, F., andBeghdadi, A. (1999): ‘Analysis of dynamic nuclear cardiac images by covariance function’,Comput. Med. Imag. Graph.,23, pp. 181–191
Boudraa, A.-O., Behloul, F., Janier, M., Canet, E., Champier, J., Roux, J.-P., andRevel, D. (2001): ‘Temporal covariance analysis of 1rst-pass contrast-enhanced myocardial magnetic resonance images’,Comput. Biol. Med.,31, pp. 133–142
Brix, G., Zaers, J., Adam, L. E., Bellemann, M. E., Ostertag, H., Trojan, H., Haberkorn, U., Doll, J., Oberdorfer, F., andLorenz, W. J. (1997): ‘Performance evaluation of a whole-body PET scanner using the NEMA protocol’,J. Nucl. Med.,38, pp. 1614–1623
Connine, C. M., Titone, D., Deelman, T., andBlasko, D. (1997): ‘Similarity mapping in spoken word recognition’,J. Memory Lang.,37, pp. 463–480
Dufournaud, Y., Schmid, C., andHoraud, R. (2004): ‘Image matching with scale adjustment’,Comput. Vis. Image Und.,93, pp. 175–194
Gambhir, S. S., Czernin, J., Schwimmer, J., Silverman, D. H. S., Coleman, E., andPhelps, M. E. (2001): ‘A tabulated summary of the FDG PET literatura’,J. Nucl. Med.,42, pp. 1S-93S
Huang, S.-C. (2000): ‘Anatomy of SUV’,Nucl. Med. Biol.,27, pp. 643–646
Hyman, T., Rothmann, C., Heller, A., Malik, Z., andSalzberg, S. (2001): ‘Structural characterization of erythroid and megakaryocytic differentiation in Friend erythroleukemia cells’,Exper. Hematol.,29, pp. 563–571
Jerusalem, G., Hustinx, R., Beguin, Y., andFillet, G. (2003): ‘PET scan imaging in oncology’,Eur. J. Cancer,39, pp. 1525–1534
Keyes, J. W. (1995): ‘SUV: standard uptake or silly useless value?’,J. Nucl. Med.,36, pp. 1836–1839
Kontaxakis, G., Strauss, L. G., Thireou, T., Ledesma-Carbayo, M. J., Santos, A., Pavlopoulos, S., andDimitrakopoulou-Strauss, A. (2002): ‘Iterative image reconstruction for clinical PET using ordered subsets, median root prior and a Web-based interface’,Mol. Imag. Biol.,4, pp. 219–231
Lapela, M., Eigtved, A., Jyrkki, S., et al., (2000): ‘Experience in qualitative and quantitative FDG PET in follow-up of patients with suspected recurrence from head and neck cancer’,Eur. J. Cancer,36, pp. 858–867
Lee, J. S., Lee, D. D., Choi, S., Park, K. S., andLee, D. S. (2001): ‘Non-negative matrix factorization of dynamic images in nuclear medicine’,IEEE Nuclear Science Symposium Conference Record,4, pp. 2027–2030
Lo, E. H., Rogowska, J., Bogorodzki, P., Trocha, M., Matsumoto, K., Saffran, B., andWolf, G. L. (1996): ‘Temporal correlation analysis of penumbral dynamics in focal cerebral ischemia’,J. Cereb. Blood Flow Metab.,16, pp. 60–68
Lucas-Quesada, F. A., Sinha, U., andSinha, S. (1996): ‘Segmentation strategies for breast tumors from dynamic MR images’,JMRI,6, pp. 753–763
Lucignani, G., Paganelli, G., andBombardieri, E. (2004): ‘The use of standardized uptake values for assessing FDG uptake with PET in oncology: a clinical perspective’,Nucl. Med. Commun.,25, pp. 651–656
Phelps, M. E. (2004): ‘PET—molecular imaging and its biological applications’, (Springer Science and Business Media, NY, 2004)
Rogowska, J., andWolf, G. L. (1992): ‘Temporal correlation images derived from sequential MR scans’,J. Comput. Assist. Tomogr.,16, pp. 784–788
Rogowska, J., Preston Jr, K., Aronen, H. J., andWolf, G. L. (1994): ‘A comparative analysis of similarity mapping and eigen-imaging as applied to dynamic MR imaging of low grade astrocytoma’,Acta Radiologica,35, pp. 371–377
Rogowska, J., Preston, K., Hunter, G. J., Hamberg, L. M., Kwong, K. K., Salonen, O., andWolf, G. L. (1995): ‘Applications of similarity mapping in dynamic MRI’,IEEE Trans. Med. Imag.,14, pp. 480–486
Rothmann, C., Levinshal, T., Timan, B., Avtalion, R. R., andMalik, Z. (2000): ‘Spectral imaging of red blood cells in experimental anemia of Cyprinus carpio’,Compar. Biochem. Physiol. A,125, pp. 75–83
Strauss, L. G., andConti, P. S. (1991): ‘The applications of PET in clinical oncology’,J. Nucl. Med.,32, pp. 623–648
Strauss, L. G. (1996): ‘F-18 deoxyglucose and false-positive results: a major problem in the diagnostics of oncological patients’,Eur. J. Nucl. Med.,23, pp. 1409–1415
Strauss, L. G., Kontaxakis, G., Dimitrakopoulou-Strauss, A., Pavlopoulos, S., andSantos LLEO, A. (1998): ‘Parametric imaging of dynamic PET studies, based on compartmental and non-compartmental approaches’,Eur. J. Nucl. Med.,25, p. 938
Strauss, L. G., Dimitrakopoulou-Strauss, A., andHaberkorn, U. (2003): ‘Shortened PET data acquisition protocol for the quantification of18F-FDG kinetics’,J. Nucl. Med.,44, pp. 1933–1939
Tanimoto, T. T. (1961): ‘A nonlinear model for a computer-assisted medical diagnostic procedure’,New York Acad. Sci. Trans. (ser. II),23, pp. 576–578
Thireou, T., Strauss, L. G., Dimitrakopoulou-Strauss, A., Kontaxakis, G., Pavlopoulos, S., andSantos, A. (2003): ‘Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer’,Comput. Med. Imaging Graphics,27, pp. 43–51
Toorongian, S. A., Mulholland, G. K., Jewett, D. M., Bachelor, M. A., andKilbourn, M. R. (1990): ‘Routine production of 2-deoxy-2(F-18)fluoro-D-glucose by direct nucleophilic exchange on a quaternary 4-amino-pyridinium resin’,Nucl. Med. Biol.,3, pp. 273–279
Venot, A., Lebruchec, J. F., andRoucayrol, J. C. (1984): ‘A new class of similarity measures for robust image registration’,Comput. Vis. Graphics Image Proc.,28, pp. 176–184
Visvikis, D., Cheze-LeRest, C., Costa, D. C., Bomanji, J., Gacinovic, S., andEll, P. J. (2001): ‘Influence of OSEM and segmented attenuation correction in the calculation of standardised uptake values for [18F]FDG PET’,Eur. J. Nucl. Med.,28, pp. 1326–1335
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Thireou, T., Kontaxakis, G., Strauss, L.G. et al. Feasibility study of the use of similarity maps in the evaluation of oncological dynamic positron emission tomography images. Med. Biol. Eng. Comput. 43, 23–32 (2005). https://doi.org/10.1007/BF02345119
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02345119