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Integrating heterogeneous datasets in genomic mapping: Radiation hybrids, YACs, genes and STS markers over the entire human chromosome X

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Bioinformatics (GCB 1996)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1278))

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Abstract

We describe an approach to integration of different types of genetic and physical mapping data for the human chromosome X, including radiation hybrids (RHs), STSs, microsatellites, genes and clones. It includes a rapid construction of the marker-RH map over the entire chromosome and a subsequent positioning of yeast artificial chromosome (YAC) clones from the data generated by YAC hybridization to RH filters or by probing YAC filters with the whole RHs.

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Author information

Authors and Affiliations

  1. Max-Planck-Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany

    Andrei Grigoriev

  2. Dept of Genome Analysis, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, WC2A 3PX, London, UK

    Johan Kumlien

  3. Max-Planck-Institute for Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany

    Hans Lehrach

Authors
  1. Andrei Grigoriev
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  2. Johan Kumlien
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  3. Hans Lehrach
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Editor information

Ralf Hofestädt Thomas Lengauer Markus Löffler Dietmar Schomburg

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© 1997 Springer-Verlag Berlin Heidelberg

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Grigoriev, A., Kumlien, J., Lehrach, H. (1997). Integrating heterogeneous datasets in genomic mapping: Radiation hybrids, YACs, genes and STS markers over the entire human chromosome X. In: Hofestädt, R., Lengauer, T., Löffler, M., Schomburg, D. (eds) Bioinformatics. GCB 1996. Lecture Notes in Computer Science, vol 1278. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0033209

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  • DOI: https://doi.org/10.1007/BFb0033209

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-63370-9

  • Online ISBN: 978-3-540-69524-0

  • eBook Packages: Springer Book Archive

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