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Classification of sleep stages using class-dependent sequential feature selection and artificial neural network

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Abstract

Several studies have been conducted for automatic classification of sleep stages to ease time-consuming manual scoring process that can involve a high degree of experience and subjectivity. But none of them has found a practical usage in medical area so far because of their under acceptable success rates. In this study, a different classification scheme is proposed to increase the success rate in automatic sleep stage scoring in which sleep stages were classified as Awake, Non-REM1, Non-REM2, Non-REM3 and REM stages. Using EEG, EMG and EOG recordings of five healthy subjects, a modified version of sequential feature selection method was applied to the sleep epochs in class by class basis and different artificial neural network (ANN) architectures were trained for each class. That is to say, sleep stages were classified with five ANN architectures each of which uses different features and different network parameters for classification. The highest classification accuracy was obtained for REM sleep as 95.13 % in addition to the lowest classification accuracy of 86.42 % for Non-REM3 sleep. The overall accuracy, on the other hand, was recorded as 90.93 %, which is a comparatively good result when the other studies using all stages are taken into account.

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References

  1. Rechtschaffen A, Kales A (1969) A manual of standardized terminology. Techniques and scoring system for sleep stages of human subjects. US Government Printing Office, Washington

    Google Scholar 

  2. AASM (1999) Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine, Task Force

  3. Holzmann CA, Pérez CA, Held CM, Martín MS, Pizarro F, Pérez JP, Garrido M, Pierano P (1999) Expert-system classification of sleep/waking states in infants. Med Biol Eng Comput 37:466–476

    Article  Google Scholar 

  4. Oropesa E, Cycon HL, Jobert M (1999) Sleep stage classification using wavelet transform and neural network. Int Comput Sci Inst, TR-99-008

  5. Agarwal R, Gotman J (2001) Computer-assisted sleep staging. IEEE Trans Biomed Eng 48:1412–1423

    Article  Google Scholar 

  6. Piñero P, Garcia P, Arco L, Álvarez A, García MM, Bonal R (2004) Sleep stage classification using fuzzy sets and machine learning techniques. Neurocomputing 58–60:1137–1143

    Article  Google Scholar 

  7. Estrada E, Nazeran H, Nava P, Behmehani K, Burk J, Lucas E (2004) EEG feature extraction for classification of sleep stages. In: Proceedings of the 26th annual conference of the IEEE EMBS, San Francisco, USA

  8. Acharya R, Faust O, Kannathal N, Chua T, Laxmirayan S (2005) Non-Linear analysis of EEG signals at various sleep stages. Comput Methods Prog Biomed 80:37–45

    Article  Google Scholar 

  9. Pereda E, Gamundi A, Rial R, González J (1998) Non-linear behavior of human EEG: fractal exponent versus correlation dimension in awake and sleep stages. Neurosci Lett 250:91–94

    Article  Google Scholar 

  10. Jiayi G, Peng Z, Xin Z, Mingshi W (2007) Sample entropy analysis of aleep EEG under different states. In: Proceedings of the IEEE/ICME international conference on complex medical Engineering, China

  11. Van Quyen ML, Chavez M, Rudrauf D, Martinerie J (2003) Exploring the nonlinear dynamics of the brain. J Physiol 97:629–639

    Google Scholar 

  12. He W-X, Yan X-G, Chen X-P, Liu H (2005) Nonlinear feature extraction of sleeping EEG signals. In: Proceedings of the 27th annual conference of IEEE engineering in medicine and biology, Shangai, China

  13. Shen Y, Olbrich E, Achermann P, Meier PF (2003) Dimensional complexity and spectral properties of the human sleep EEG. Clin Neurophysiol 114:199–209

    Article  Google Scholar 

  14. Becq G, Charbonnier S, Chapotot F, Buguet A, Bourdon L, Baconnier P (2005) Comparison between five classifiers for automatic scoring of human sleep recordings. Stud Comput Intell 4:113–127

    Google Scholar 

  15. Flexer A, Gruber G, Dorffner G (2005) A reliable probabilistic sleep stager based on a single EEG signal. Artif Intell Med 33:199–207

    Article  Google Scholar 

  16. Sinha RK (2008) Artificial neural network and wavelet based automated detection of sleep spindles, REM sleep and wake states. J Med Syst 32:291–299

    Article  Google Scholar 

  17. Šušmáková K, Krakovská A (2008) Discrimination ability of individual measures used in sleep stages classification. Artif Intell Med 44:261–277

    Article  Google Scholar 

  18. Chapotot F, Becq G (2009) Automated sleep-wake staging combining robust feature extraction, artificial neural network classification, and flexible decision rules. Int J Adap Cont Signal Process

  19. Kurt MB, Sezgin N, Akin M, Kirbas G, Bayram M (2009) The ANN-based computing of drowsy level. Exp Syst Appl 36:2534–2542

    Article  Google Scholar 

  20. Jo HG, Park JY, Lee CK, An SK, Yoo SK (2010) Genetic fuzzy classifier for sleep stage identification. Comput Biol Med 40:629–634

    Article  Google Scholar 

  21. Karlik B (1999) Differentiating type of muscle movement via AR modeling and neural network classification. Turk J Elec Eng Comput Sci 7:45–52

    Google Scholar 

  22. Welch PD (1967) The use of fast fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodograms. IEEE Trans Audio Electroacoust 15:70–73

    Article  MathSciNet  Google Scholar 

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Acknowledgments

This study is supported by the Scientific Research Projects of Selcuk University (project no. 05401069).

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The authors declare that they have no conflict of interest.

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Correspondence to Seral Özşen.

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Özşen, S. Classification of sleep stages using class-dependent sequential feature selection and artificial neural network. Neural Comput & Applic 23, 1239–1250 (2013). https://doi.org/10.1007/s00521-012-1065-4

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  • DOI: https://doi.org/10.1007/s00521-012-1065-4

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