Abstract
This study first considers the effects of “uninfectious” HIV-1 due to fatal mutations, and then analysis reveals that AIDS develops when the number of HIV-1 strains, i.e., antigenic diversity, is above a “time-dependent” threshold. This result is interesting because it suggests the possibility that the onset of AIDS could be dynamically determined. This dynamic behavior of the threshold may make the prediction of AIDS development difficult.
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This work was presented in part at the 14th International Symposium on Artificial Life and Robotics, Oita, Japan, February 5–7, 2009
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Harada, K., Ishida, Y. A time-dependent threshold condition to determine the onset of AIDS. Artif Life Robotics 14, 532–534 (2009). https://doi.org/10.1007/s10015-009-0737-3
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DOI: https://doi.org/10.1007/s10015-009-0737-3