Abstract
The visual response of a cell in the primary visual cortex (V1) to a drifting grating stimulus at the cell’s preferred orientation decreases when a second, perpendicular, grating is superimposed. This effect is called masking. To understand the nonlinear masking effect, we model the response of Macaque V1 simple cells in layer 4Cα to input from magnocellular Lateral Geniculate Nucleus (LGN) cells. The cortical model network is a coarse-grained reduction of an integrate-and-fire network with excitation from LGN input and inhibition from other cortical neurons. The input is modeled as a sum of LGN cell responses. Each LGN cell is modeled as the convolution of a spatio-temporal filter with the visual stimulus, normalized by a retinal contrast gain control, and followed by rectification representing the LGN spike threshold. In our model, the experimentally observed masking arises at the level of LGN input to the cortex. The cortical network effectively induces a dynamic threshold that forces the test grating to have high contrast before it can overcome the masking provided by the perpendicular grating. The subcortical nonlinearities and the cortical network together account for the masking effect.
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Acknowledgements
M.K. gratefully acknowledges support from NEI Computational Training Grant T32 EY 7158, and R.S. acknowledges support from the Sloan and Swartz Foundations for the NYU Theoretical Neuroscience Program.
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Action Editor: Jonathan D. Victor
Melinda Koelling is formerly from Center for Neural Science and Courant Institute, New York University.
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Koelling, M., Shapley, R. & Shelley, M. Retinal and cortical nonlinearities combine to produce masking in V1 responses to plaids. J Comput Neurosci 25, 390–400 (2008). https://doi.org/10.1007/s10827-008-0086-6
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DOI: https://doi.org/10.1007/s10827-008-0086-6