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Comparing Methods for Determining Motor-Hand Lateralization Based on fTCD Signals

  • Patient Facing Systems
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Abstract

The lateralization index (LI) as determined from functional transcranial Doppler sonography (fTCD) can be used to determine the hemispheric organization of neural activation during a behavioral task. Previous studies have proposed different methods to determine this index, but to our knowledge no studies have compared the performance of these methods. In this study, we compare two established methods with a simpler method proposed here. The aim was to see whether similar results could be achieved with a simpler method and to give an indication of the analysis steps required to determine the LI. A simple unimanual motor task was performed while fTCD was acquired, and the LI determined by each of these methods was compared. In addition, LI determined by each method was related to behavioural output in the form of degree of handedness. The results suggest that although the methods differed in complexity, they yielded similar results when determining the lateralization of motor functions, and its correlation with behavior. Further investigation is needed to expand the conclusions of this preliminary study, however the new method proposed in the paper has great potential as it is much simpler than the more established methods yet yields similar results.

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Acknowledgments

This study was carried out with funding support from support CAPES (Coordination for the Improvement of Higher Education Personnel, Brazil) and FAPESP – Brazil.

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Authors and Affiliations

  1. Center for Engineering, Modeling and Applied Social Sciences, Universidade Federal do ABC, Rua Santa Adélia, 166 - Bairro Bangu, Santo André, SP, CEP 09.210-170, Brazil

    Walter H. L. Pinaya & Francisco J. Fraga

  2. Department of Neurology, Hospital das Clinicas/São Paulo University, Avenida Dr. Eneas de Carvalho Aguiar, 255/5080 - Cerqueira Cesar, São Paulo, SP, CEP 05403-000, Brazil

    Salo S. Haratz & Adriana B. Conforto

  3. Department of Psychology, University of Surrey, GU2 7XH – Guildford, Surrey, UK

    Philip J. A. Dean

  4. Department of Neurosurgery, Hospital das Clinicas/São Paulo University, Avenida Dr. Eneas de Carvalho Aguiar, 255/5080 - Cerqueira Cesar, São Paulo, SP, CEP 05403-000, Brazil

    Edson Bor-Seng-Shu & Manoel J. Teixeira

  5. Instituto Israelita de Ensino e Pesquisa Albert Einstein, Avenida Professor Francisco Morato, 4293 – Vila Sônia, São Paulo, SP, CEP 05521-000, Brazil

    Adriana B. Conforto

  6. Center for Mathematics, Computation, and Cognition, Universidade Federal do ABC, Rua Santa Adélia, 166 - Bairro Bangu, Santo André, SP, CEP 09.210-170, Brazil

    João R. Sato

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  1. Walter H. L. Pinaya
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Correspondence to Walter H. L. Pinaya.

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Pinaya, W.H.L., Fraga, F.J., Haratz, S.S. et al. Comparing Methods for Determining Motor-Hand Lateralization Based on fTCD Signals. J Med Syst 39, 4 (2015). https://doi.org/10.1007/s10916-014-0185-z

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  • DOI: https://doi.org/10.1007/s10916-014-0185-z

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