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Construction and Recognition of Functional Brain Network Model Based on Depression

  • Systems-Level Quality Improvement
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Abstract

In order to make a deep analysis of depression, the construction and recognition of functional brain network model based on depression is mainly studied. Firstly, the relevant information of the subjects is introduced in turn. The data of fMRI (functional magnetic resonance imaging) are pretreated, static and dynamic functional connections are analyzed, statistical analysis and testing are carried out, and then the results are analyzed and discussed. The results show that static functional connectivity provides a new research perspective and means for further understanding the connection patterns of brain functional networks in unipolar depression and bipolar depression. Dynamic functional connectivity analysis (DFA) extends the previous studies on unipolar depression and bipolar depression, and provides a potential biological marker for clinical identification of unipolar depression and bipolar depression.

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Authors and Affiliations

  1. Psychiatry Department, Qingdao Mental Health Center, Qingdao, 266034, Shandong, China

    Lin Wen & Yurong Cao

  2. Special Inspection Section, Qingdao Mental Health Center, Qingdao, 266034, Shandong, China

    Shan Liu

  3. Clinical Psychology, Qingdao Mental Health Center, No.295 Nanjing Road, Qingdao, 266034, Shandong, China

    Guiling Li

Authors
  1. Lin Wen
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  2. Shan Liu
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  3. Yurong Cao
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  4. Guiling Li
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Correspondence to Guiling Li.

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Conflict of Interest

Author Lin Wen declares that he has no conflict of interest. Author Shan Liu declares that he has no conflict of interest. Author Yurong Cao declares that he has no conflict of interest. Author Guiling Li declares that he has no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Wen, L., Liu, S., Cao, Y. et al. Construction and Recognition of Functional Brain Network Model Based on Depression. J Med Syst 43, 236 (2019). https://doi.org/10.1007/s10916-019-1198-4

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  • DOI: https://doi.org/10.1007/s10916-019-1198-4

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