Abstract
In order to explore the relationship between hippocampal structure changes and performance symptoms as well as cognitive function in adolescent schizophrenia, taking the brain response signals of psychiatric patients as the research object, the relationship between hippocampal volume drawn by schizophrenia and language memory of negative symptoms is explored based on morphological analysis method. It is found that the left hippocampal volume of schizophrenic patients is abnormal when the whole brain volume is returned, which is significantly lower than that of normal people. It is also found that the left hippocampus volume of schizophrenic patients is a mediator between negative symptoms and speech memory. The results show that the left hippocampus of schizophrenic patients plays an important role in the pathogenesis of schizophrenia.
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Author Xiaohui Zhi declares that he has no conflict of interest. Author Lin Cai declares that he has no conflict of interest. Author Na Guo declares that he has no conflict of interest. Author Xuejia Liu declares that he has no conflict of interest.
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Zhi, X., Cai, L., Guo, N. et al. Discussion on Brain Structure and Function in Schizophrenia by Multimodal Magnetic Resonance Imaging. J Med Syst 43, 89 (2019). https://doi.org/10.1007/s10916-019-1213-9
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DOI: https://doi.org/10.1007/s10916-019-1213-9