Skip to main content
Log in

Advances in the Visualization and the Study of the Pyramidal Tract with Magnetic Resonance Tractography

  • Education & Training
  • Published:
Journal of Medical Systems Aims and scope Submit manuscript

Abstract

Over the last several years, specific radiological techniques have been used for the analysis of the central nervous system pathways. They involve a magnetic resonance sequence called diffusion tensor imaging. In order to process the data provided by this sequence it is necessary to use software that can post-process the image and render three-dimensional images of the central nervous system pathways. Thanks to this sequence it has been possible to isolate over the years many nerve pathways that cross the brain tissue, particularly those which occupy a significant space. This sequence could have a large variety of uses, such as helping with the study of brain anatomy, assisting with surgery planning, or establishing a relationship between the nerve fibers and tumoral lesions. However, there has been an increasing number of cases that report a low reliability related to the tractographic representation of this technique. Our goal with this article is to analyse a specific nerve pathway, the piramidal tract, in order to assess the coherence between the images obtained and the anatomy that is already known from the perspective of the radiological image, and to compare this tract between different patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Johansen-Berg, H., and Behrens, T. E., Just pretty pictures? What diffusion tractography can add in clinical neuroscience. Curr Opin Neurol 19(4):379–385, 2006.

    Article  Google Scholar 

  2. Lazar, M., Mapping brain anatomical connectivity using white matter tractography. NMR Biomed 23(7):821–835, 2010. https://doi.org/10.1002/nbm.1579.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Dauguet, J., Peled, S., Berezovskii, V., Delzescaux, T., Warfield, S. K., Born, R., and Westin, C. F., Comparison of fiber tracts derived from in-vivo DTI tractography with 3D histological neural tract tracer reconstruction on a macaque brain. Neuroimage 37(2):530–538, 2007 Epub 2007 May 24.

    Article  Google Scholar 

  4. Mukherjee, P., and McKinstry, R. C., Diffusion tensor imaging and tractography of human brain development. Neuroimaging Clin N Am. 16(1):19–43, 2006 vii.

    Article  Google Scholar 

  5. Goh, S. Y., Irimia, A., Torgerson, C. M., Tubi, M. A., Real, C. R., Hanley, D. F., Martin, N. A., Vespa, P. M., and Van Horn, J. D., Longitudinal quantification and visualization of intracerebral hemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Brain Inj. 29(4):438–445, 2015. https://doi.org/10.3109/02699052.2014.989907.

    Article  PubMed  Google Scholar 

  6. Golby, A. J., Kindlmann, G., Norton, I., Yarmarkovich, A., Pieper, S., and Kikinis, R., Interactive diffusion tensor Tractography visualization for neurosurgical planning. Neurosurgery 68(2):496–505, 2011. https://doi.org/10.1227/NEU.0b013e3182061ebb.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Jellison, B. J., Field, A. F., Medow, J., Lazar, M., Salamat, M. S., and Alexander, A. L., Diffusion tensor imaging of cerebral white matter: A pictorial review of Phisics, Fiber tract anatomy, and tumor imaging patterns. AJNR Am J Neuroradiol 25:356–369, 2004.

    PubMed  Google Scholar 

  8. Essayed, W. I., Zhang, F., Unadkat, P., Cosgrove, G. R., Golby, A. J., and O'Donnell, L. J., White matter tractography for neurosurgical planning: A topography-based review of the current state of the art. Neuroimage Clin. 15:659–672, 2017. https://doi.org/10.1016/j.nicl.2017.06.011.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Feigl, G. C., Hiergeist, W., Fellner, C., Schebesch, K. M., Doenitz, C., Finkenzeller, T., Brawanski, A., and Schlaier, J., Magnetic resonance imaging diffusion tensor Tractography: Evaluation of anatomic accuracy of different Fiber tracking software packages. World Neurosurg. 81(1):144–150, 2014. https://doi.org/10.1016/j.wneu.2013.01.004. Epub 2013 Jan 4.

    Article  PubMed  Google Scholar 

  10. Schilling, K. G., Daducci, A., Maier-Hein, K., Poupon, C., Houde, J. C., Nath, V., Anderson, A. W., Landman, B. A., and Descoteaux, M., Challenges in diffusion MRI tractography – Lessons learned from international benchmark competitions. Magn Reson Imaging S0730-725X(18)30516-2, 2019. https://doi.org/10.1016/j.mri.2018.11.014.

    Article  Google Scholar 

  11. Schilling, K. G., Nath, V., Hansen, C., Parvathaneni, P., Blaber, J., Gao, Y., Neher, P., Aydogan, D. B., Shi, Y., Ocampo-Pineda, M., Schiavi, S., Daducci, A., Girard, G., Barakovic, M., Rafael-Patino, J., Romascano, D., Rensonnet, G., Pizzolato, M., Bates, A., Fischi, E., Thiran, J. P., Canales-Rodríguez, E. J., Huang, C., Zhu, H., Zhong, L., Cabeen, R., Toga, A. W., Rheault, F., Theaud, G., Houde, J. C., Sidhu, J., Chamberland, M., Westin, C. F., Dyrby, T. B., Verma, R., Rathi, Y., Irfanoglu, M. O., Thomas, C., Pierpaoli, C., Descoteaux, M., Anderson, A. W., and Landman, B. A., Limits to anatomical accuracy of diffusion tractography using modern approaches. Neuroimage 185:1–11, 2018. https://doi.org/10.1016/j.neuroimage.2018.10.029.

    Article  PubMed  Google Scholar 

  12. Jbabdi S, Johansen-Berg H (2011) Tractography: Where Do We Go from Here?. Brain Connect. Volume 1, Number 3, Mary Ann Liebert, Inc. DOI:https://doi.org/10.1089/brain.2011.0033.

    Article  Google Scholar 

  13. Min, Z. G., Rana, N., Niu, C., Ji, H. M., and Zhang, M., Does diffusion tensor tractography of the corticospinal tract correctly reflect motor function? Med Princ Pract. 23(2):174–176, 2014. https://doi.org/10.1159/000353463. Epub 2014 Aug 13.

    Article  PubMed  Google Scholar 

  14. Mandelli, M. L., Berger, M. S., Bucci, M., Berman, J. I., Amirbekian, B., and Henry, R. G., Quantifying accuracy and precision of diffusion MR tractography of the corticospinal tract in brain tumors. J Neurosurg. 121(2):349–358, 2014. https://doi.org/10.3171/2014.4.JNS131160. Epub 2014 Jun 6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Katrin Muradas Mujika.

Ethics declarations

Conflict of interest

Katrin Muradas Mujika declares that she has no conflict of interest. Juan Antonio Juanes Méndez declares that he has no conflict of interest. Andrés Framiñán de Miguel declares that he has no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Education & Training

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Muradas Mujika, K., Juanes Méndez, J.A. & Framiñan de Miguel, A. Advances in the Visualization and the Study of the Pyramidal Tract with Magnetic Resonance Tractography. J Med Syst 43, 106 (2019). https://doi.org/10.1007/s10916-019-1242-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10916-019-1242-4

Keywords

Navigation