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Deep transfer learning for alzheimer neurological disorder detection

  • 1155T: Advanced machine learning algorithms for biomedical data and imaging
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Abstract

Alzheimer’s disease is becoming common in the world with the time. It is an irreversible and progressive brain disorder that slowly destroys the memory and thinking skills and, eventually, the ability to perform the simplest tasks. It becomes severe before the noticeable symptoms appear and causes brain disorder which cannot be cured by any medicines and therapies, however its progression can be slow down through early diagnosis. In this paper, we employed different CNN based transfer learning methods for Alzheimer disease classification. We have applied different parameters, and achieved remarkable accuracy on benchmark ADNI dataset. We have tested 13 differnt flavours of different pre-trained CNN models using a fine-tuned approach of transfer learning across two different domain on ADNI dataset (94 AD, 138 MCI and 146 NC). Comparatively, DenseNet showed better performance by achieving a maximal average accuracy of % 99.05. Significant improvement in accuracy has been observed as compared to previously reported works in terms of specificity, sensitivity and accuracy. The source code of propose framework is publicly available.

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Authors and Affiliations

  1. GGPGC No.1, Abbottabad, Pakistan

    Abida Ashraf & Saeeda Naz

  2. Department of IT, Hazara University, Mansehra, Pakistan

    Syed Hamad Shirazi

  3. Deakin University, Geelong, Australia

    Imran Razzak

  4. University of Technology, Sydney, Australia

    Mukesh Parsad

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  1. Abida Ashraf
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  2. Saeeda Naz
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  3. Syed Hamad Shirazi
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  4. Imran Razzak
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  5. Mukesh Parsad
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Correspondence to Imran Razzak.

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https://github.com/imranrazzak/Neurological-Disorder

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Ashraf, A., Naz, S., Shirazi, S.H. et al. Deep transfer learning for alzheimer neurological disorder detection. Multimed Tools Appl 80, 30117–30142 (2021). https://doi.org/10.1007/s11042-020-10331-8

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  • DOI: https://doi.org/10.1007/s11042-020-10331-8

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