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Design and wet-laboratory implementation of reliable end-to-end molecular communication

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Abstract

This paper describes a novel design and wet laboratory implementation of reliable end-to-end molecular communication. In the reliable end-to-end molecular communication described in this paper, source and destination bio-nanomachines exchange molecular packets through intermediate bio-nanomachines that are capable of packet replication. A source bio-nanomachine forms a molecular packet and transmits the molecular packet into the environment. An intermediate bio-nanomachine detects a molecular packet and produces its copies through packet replication. A destination bio-nanomachine, upon reception of a molecular packet, produces an acknowledgment molecular packet and transmits back to the source bio-nanomachine. This paper describes how the reliable end-to-end molecular communication can be biochemically implemented with RNA (ribonucleic acid) molecules and artificial cell systems. It also describes a simulation-based performance evaluation study showing the impact of model parameters on propagation delay in the reliable end-to-end molecular communication.

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Notes

  1. INFO-RNA and ACK-RNA have different header lengths. An INFO-RNA is longer than an ACK-RNA.

  2. INFO-RNA and ACK-RNA described in Sect. 3 consist of approximately 2,000 and 200 nucleotides, respectively.

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Acknowledgements

This work was supported through the Osaka University Humanware Innovation Program, a Leading Graduate School Program by the Japan Society of the Promotion of Science. This work was also supported by JSPS KAKENHI Grant Number JP25240011.

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Authors and Affiliations

  1. Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan

    Taro Furubayashi & Tadashi Nakano

  2. Graduate School of Information Science and Technology, Osaka University, Osaka, Japan

    Yoshihiro Sakatani & Norikazu Ichihashi

  3. Department of Electrical Engineering and Computer Science, York University, Toronto, Canada

    Andrew Eckford

Authors
  1. Taro Furubayashi
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  2. Yoshihiro Sakatani
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  3. Tadashi Nakano
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  4. Andrew Eckford
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  5. Norikazu Ichihashi
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Correspondence to Tadashi Nakano.

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Furubayashi, T., Sakatani, Y., Nakano, T. et al. Design and wet-laboratory implementation of reliable end-to-end molecular communication. Wireless Netw 24, 1809–1819 (2018). https://doi.org/10.1007/s11276-016-1435-4

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