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Pulmonary nodule detection based on IR-UNet +  + 

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Abstract

Lung cancer is one of the cancers with the highest incidence rate and death rate worldwide. An initial lesion of the lung appears as nodules in the lungs on CT images, and early and timely diagnosis can greatly improve the survival rate. Automatic detection of lung nodules can greatly improve work efficiency and accuracy rate. However, owing to the three-dimensional complex structure of lung CT data and the variation in shapes and appearances of lung nodules, high-precision detection of pulmonary nodules remains challenging. To address the problem, a new 3D framework IR-UNet +  + is proposed for automatic pulmonary nodule detection in this paper. First, the Inception Net and ResNet are combined as the building blocks. Second, the squeeze-and-excitation structure is introduced into building blocks for better feature extraction. Finally, two short skip pathways are redesigned based on the U-shaped network. To verify the effectiveness of our algorithm, systematic experiments are conducted on the LUNA16 dataset. Experimental results show that the proposed network performs better than several existing lung nodule detection methods with the sensitivity of 1 FP/scan, 4 FPs/scan, and 8 FPs/scan being 90.13%, 94.77%, and 95.78%, respectively. Therefore, it comes to the conclusion that our proposed model has achieved superior performance for lung nodule detection.

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Funding

This work was supported by the Zhejiang Provincial Natural Science Foundation of China (No. LZ22F010003), the National Natural Science Foundation of China (No. 61871427), and the National Key R&D Program of China (2021ZD0113204).

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  1. School of Automation, Hangzhou Dianzi University, Hangzhou, 310018, China

    Jingchao Lin, Qingshan She & Yun Chen

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  1. Jingchao Lin
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Correspondence to Qingshan She or Yun Chen.

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Lin, J., She, Q. & Chen, Y. Pulmonary nodule detection based on IR-UNet +  + . Med Biol Eng Comput 61, 485–495 (2023). https://doi.org/10.1007/s11517-022-02727-5

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