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Respiratory liver motion simulator for validating image-guided systems ex-vivo

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Objective:

A clinically realistic phantom incorporating respiratory motion was developed for validating image-guided systems for the liver.

Materials and methods:

The respiratory liver motion simulator consists of a physical human torso model which allows for an explanted human or porcine liver to be mounted adjacent to an artificial diaphragm. The apparatus can be connected to a lung ventilator for simulation of respiratory motion and is compatible with computed tomography (CT) and magnetic resonance imaging (MRI). To analyze the liver movement generated by the simulator, we examined three porcine livers mounted to the phantom and monitored their movement with a set of optically tracked fiducial needles.

Results:

Mean displacement between expiration and inspiration was 15.0 ± 4.7 mm, with craniocaudal movement making up the main part (14.2 ± 4.9 mm). In addition, the livers showed movement due to tissue deformation.

Conclusion:

The liver movement generated by the motion simulator is comparable to that of a human liver in vivo. The phantom thus provides a low-cost alternative to animal experiments for validating image-guided systems.

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Authors and Affiliations

  1. Division of Medical and Biological Informatics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany

    L. Maier-Hein, U. Rietdorf, A. Seitel, A. M. Franz, I. Wolf & H.-P. Meinzer

  2. Department of General, Abdominal and Transplant Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany

    F. Pianka, S. A. Müller & B. M. Schmied

Authors
  1. L. Maier-Hein
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  2. F. Pianka
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  3. S. A. Müller
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  4. U. Rietdorf
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  5. A. Seitel
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  6. A. M. Franz
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  7. I. Wolf
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  8. B. M. Schmied
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  9. H.-P. Meinzer
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Correspondence to L. Maier-Hein.

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Maier-Hein, L., Pianka, F., Müller, S.A. et al. Respiratory liver motion simulator for validating image-guided systems ex-vivo. Int J CARS 2, 287–292 (2008). https://doi.org/10.1007/s11548-007-0140-2

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  • DOI: https://doi.org/10.1007/s11548-007-0140-2

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