Skip to main content
Log in

First clinical experience in applying XperGuide in embolization of jugular paragangliomas by direct intratumoral puncture

  • Original Article
  • Published:
International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

The purpose of this study is to introduce a novel image-guided technique utilized in the embolization of jugular paraganglioma tumors, using preoperative diagnostic scans and planning together with perioperative X-ray fluoroscopy in a combined image.

Methods

A lesion center and a skin entry point on the patient are selected and connected with a straight line, which resembles the most ideal lesion access trajectory to be followed during the needle insertion. The skin entry point and the corresponding line location are selected such that it avoids the impenetrable bones and vital anatomical structures. Two viewing incidence angles are defined to guide the cranial needle insertion: the entry view tangent to the planned trajectory, and the progression view perpendicular to the path.

Results

The proposed method was applied in two patients with jugular paragangliomas in order to navigate needles to the lesion location and subsequently embolize the tumors. The perioperative registration took less than 8 s. Using this method, it was possible to guide the needle within 5 mm of the planned path.

Conclusion

The fluoroscopic needle navigation, overlaid on the corresponding soft tissue of the underlying anatomy, combined with a planned path, has been shown to be an accurate and efficient tool for needle guidance. The patient pose varied between the preoperative data and the fluoroscopy guided intervention, but this did not hinder the procedure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Erickson D, Kudva YC, Ebersold MJ et al (2001) Benign paragangliomas: clinical presentation and treatment outcomes in 236 patients. J Clin Endocrinol Metab 86: 5210–5216. doi:10.1210/jc.86.11.5210

    Article  CAS  PubMed  Google Scholar 

  2. van den Berg G, Rodesch G, Lasjaunias P (2002) Management of paragangliomas: clinical and angiographic aspects. Intervent Neuroradiol 8: 127–134

    Google Scholar 

  3. Somasundar P, Krouse R, Hostetter R et al (2000) Paragangliomas: a decade of clinical experience. J Surg Oncol 74: 286–290. doi:10.1002/1096-9098(200008)74:4<286::AID-JSO9>3.0.CO;2-C

    Article  CAS  PubMed  Google Scholar 

  4. Patetsios P, Gable DR, Garrett WV et al (2002) Management of carotid body paragangliomas and review of a 30-year experience. Ann Vasc Surg 16: 331–338. doi:10.1007/s10016-001-0106-8

    Article  PubMed  Google Scholar 

  5. Muhm M, Polterauer P, Gstottner W et al (1997) Diagnostic and therapeutic approaches to carotid body tumors. Review of 24 patients. Arch Surg 132: 279–284

    CAS  PubMed  Google Scholar 

  6. Leonetti JP, Donzelli JJ, Littooy FN et al (1997) Perioperative strategies in the management of carotid body tumors. Otolaryngol Head Neck Surg 117: 111–115. doi:10.1016/S0194-5998(97)70216-X

    Article  CAS  PubMed  Google Scholar 

  7. Brown JS (1985) Glomus jugulare tumors revisited: a ten-year statistical follow-up of 231 cases. Laryngoscope 95: 284–288. doi:10.1288/00005537-198503000-00008

    Article  CAS  PubMed  Google Scholar 

  8. Sniezek JC, Sabri AN, Netterville JL (2001) Paraganglioma surgery: complications and treatment. Otolaryngol Clin North Am 34: 993–1006. doi:10.1016/S0030-6665(05)70359-5

    Article  CAS  PubMed  Google Scholar 

  9. Persky MS, Niimi ASY et al (2002) Combined endovascular and surgical treatment of head and neck paragangliomasa team approach. Head Neck 24: 423–431. doi:10.1002/hed.10068

    Article  PubMed  Google Scholar 

  10. Gruber A, Bavinzski G, Killer M et al (2000) Preoperative embolization of hypervascular skull base tumors. Minim Invasive Neurosurg 43: 62–71. doi:10.1055/s-2000-8321

    Article  CAS  PubMed  Google Scholar 

  11. Tikkakoski T, Luotonen J, Leinonen S et al (1997) Preoperative embolization in the management of neck paragangliomas. Laryngoscope 107: 821–826. doi:10.1097/00005537-199706000-00018

    Article  CAS  PubMed  Google Scholar 

  12. Murphy TP, Brackmann DE (1989) Effects of preoperative embolization on glomus jugulare tumors. Laryngoscope 99: 1244–1247. doi:10.1288/00005537-198912000-00007

    Article  CAS  PubMed  Google Scholar 

  13. Valavanis A (1986) Preoperative embolization of the head and neck: indications, patient selection, goals, and precautions. AJNR Am J Neuroradiol 7: 943–952

    CAS  PubMed  Google Scholar 

  14. Pierot L, Boulin A, Castaings L et al (1994) Embolization by direct puncture of hypervascularized ORL tumors. Ann Otolaryngol Chir Cervicofac 111: 403–409

    CAS  PubMed  Google Scholar 

  15. Casasco A, Herbreteau D, Houdart E et al (1994) Devascularization of craniofacial tumors by percutaneous tumor puncture. Neurosurgery 15: 1233–1239

    CAS  Google Scholar 

  16. Chaloupka JC, Mangla S, Huddle DC et al (1999) Evolving experience with direct puncture therapeutic embolization for adjunctive and palliative management of head and neck hypervascular neoplasms. Laryngoscope 109: 1864–1872. doi:10.1097/00005537-199911000-00028

    Article  CAS  PubMed  Google Scholar 

  17. Casasco A, Houdart E, Biondi A et al (1999) Major complications of percutaneous embolization of skull-base tumors. AJNR Am J Neuroradiol 20: 179–181

    CAS  PubMed  Google Scholar 

  18. Leonardi M, Barbara C, Simmonetti L et al (2002) Glubran 2: a new acrylic glue for neuroradiological endovascular use. Intervent Neuroradiol 8: 245–250

    Google Scholar 

  19. Giansante Abud D, Mounayer C, Benndorf G, Piotin M, Spelle L, Moret J (2004) Intratumoral injection of cyanoacrylate glue in head and neck paragangliomas. AJNR Am J Neuroradiol 25: 1457–1462

    Google Scholar 

  20. Racadio JM, Babic D, Homan R, Rampton JW, Patel MN, Racadio JM, Johnson ND (2007) Live 3D guidance in the interventional radiology suite. AJR Am J Roentgenol 189: W357–W364. doi:10.2214/AJR.07.2469

    Article  PubMed  Google Scholar 

  21. Maes F, Collignon A, Vandermeulen D, Marchal G, Suetens P (1997) Multimodality image registration by maximization of mutual information. IEEE Trans Med Imaging 16(2): 187–198. doi:10.1109/42.563664

    Article  CAS  PubMed  Google Scholar 

  22. Maeda N, Osuga K, Higashihara H, Tomoda K, Nakamura H (2008) A novel conebeam CT guided interventions by XperGuide: Accuracy and feasibility in a phantom model. JVIR 19(2), Suppl 1:S90 doi:10.1016/j.jvir.2007.12.263

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Ruijters.

Electronic Supplementary Material

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spelle, L., Ruijters, D., Babic, D. et al. First clinical experience in applying XperGuide in embolization of jugular paragangliomas by direct intratumoral puncture. Int J CARS 4, 527–533 (2009). https://doi.org/10.1007/s11548-009-0370-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11548-009-0370-6

Keywords

Navigation