Skip to main content

Advertisement

Log in

Fast and robust extraction of surrogate respiratory signal from intra-operative liver ultrasound images

  • Original Article
  • Published:
International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

   In model-based respiratory motion estimation for the liver or other abdominal organs, the surrogate respiratory signal is usually obtained by using special tracking devices from skin or diaphragm, and subsequently applied to parameterize a 4D motion model for prediction or compensation. However, due to the intrinsic limits and economical costs of these tracking devices, the identification of the respiratory signal directly from intra-operative ultrasound images is a more attractive alternative.

Methods

   We propose a fast and robust method to extract the respiratory motion of the liver from an intra-operative 2D ultrasound image sequence. Our method employs a preprocess to remove speckle-like noises in the ultrasound images and utilizes the normalized cross-correlation to measure the image similarity fast. More importantly, we present a novel adaptive search strategy, which makes full use of the inter-frame dependency of the image sequence. This search strategy narrows the search range of the optimal matching, thus greatly reduces the search time, and makes the matching process more robust and accurate.

Results

   The experimental results on four volunteers demonstrate that our method is able to extract the respiratory signal from an image sequence of 256 image frames in 5 s. The quantitative evaluation using the correlation coefficient reveals that the respiratory motion, extracted near the liver boundaries and vessels, is highly consistent with the reference motion tracked by an EM device.

Conclusions

   Our method can use 2D ultrasound to track natural landmarks from the liver as surrogate respiratory signal and hence provide a feasible solution to replace special tracking devices.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

Notes

  1. http://www.liversuite.com/.

References

  1. Beasley RA (2012) Medical robots: current systems and research directions. J Robot 2012:1–14

  2. Ho H, Yuen JSP, Cheng CWS (2011) Robotic prostate biopsy and its relevance to focal therapy of prostate cancer. Nat Rev Urol 8:579–585

    Article  PubMed  Google Scholar 

  3. von Siebenthal M (2008) Analysis and modelling of respiratory liver motion using 4DMRI. Dissertation, ETH Zurich

  4. Bruder R, Ernst F, Schlaefer A, Schweikard A (2011) A framework for real-time target tracking in radiosurgery using three-dimensional ultrasound. In: CARS 2011, pp S306–S307

  5. Nadeau C, Krupa A, Gangloff J (2011) Automatic tracking of an organ section with an ultrasound probe: compensation of respiratory motion. In: Fichtinger G, Martel A, Peters T (eds) MICCAI 2011. Springer, Berlin, pp 57–64

  6. McClelland JR, Hawkes DJ, Schaeffter T, King AP (2013) Respiratory motion models: a review. Med Image Anal 17:19–42

    Article  PubMed  CAS  Google Scholar 

  7. Rohlfing T, Maurer CR, O’Dell WG, Zhong J (2004) Modeling liver motion and deformation during the respiratory cycle using intensity-based nonrigid registration of gated MR images. Medical Phys 31:427–432

    Article  Google Scholar 

  8. Rijkhorst E-J, Heanes D, Odille F, Hawkes D, Barratt D (2010) Simulating dynamic ultrasound using MR-derived motion models to assess respiratory synchronisation for image-guided liver interventions. In: Navab N, Jannin P (eds) IPCAI 2010. Springer, Berlin, pp 113–123

  9. Rijkhorst E-J, Rivens I, Ter Haar G, Hawkes D, Barratt D (2011) Effects of respiratory liver motion on heating for gated and model-based motion-compensated high-intensity focused ultrasound ablation. In: Fichtinger G, Martel A, Peters T (eds) MICCAI 2011. Springer, Heidelberg, pp 605–612

  10. Preiswerk F, Arnold P, Fasel B, Cattin PC (2011) A Bayesian framework for estimating respiratory liver motion from sparse measurements. In: Yoshida H, Sakas G, Linguraru M (eds) MICCAI 2011. Springer, Heidelberg, pp 207–214

  11. Arnold P, Preiswerk F, Fasel B, Salomir R, Scheffler K, Cattin PC (2011) 3D organ motion prediction for MR-guided high intensity focused ultrasound. In: Yoshida H, Sakas G, Linguraru M (eds) MICCAI 2011. Springer, Heidelberg, pp 623–30

  12. Preiswerk F, Arnold P, Fasel B, Cattin PC (2012) Robust tumour tracking from 2D imaging using a population-based statistical motion model. In: IEEE workshop on mathematical methods in biomedical image, analysis. pp 209–214

  13. Khamene A, Warzelhan J, Vogt S, Elgort D, Chefd’Hotel C, Duerk J, Lewin J, Wacker F, Sauer F (2004) Characterization of Internal Organ Motion Using Skin Marker Positions. In: Barillot C, Haynor D, Hellier P (eds) MICCAI 2004. Springer, Berlin, pp 526–533

  14. Ernst F, Martens V, Schlichting S, Besirević A, Kleemann M, Koch C, Petersen D, Schweikard A (2009) Correlating chest surface motion to motion of the liver using epsilon-SVR-a porcine study. In: MICCAI 2009. Springer, Berlin, pp 356–64

  15. Ernst F, Bruder R, Schlaefer A, Schweikard A (2012) Correlation between external and internal respiratory motion: a validation study. Int J Comput Assist Radiol Surg 7(3):483–492

    Google Scholar 

  16. Pluim JPW, Maintz JBA, Viergever MA (2003) Mutual-information-based registration of medical images: a survey. IEEE Trans Med Imaging 22:986–1004

    Article  PubMed  Google Scholar 

  17. Tsai D-M, Lin C-T, Chen J-F (2003) The evaluation of normalized cross correlations for defect detection. Pattern Recognit Lett 24:2525–2535

    Article  Google Scholar 

Download references

Acknowledgments

Conflict of Interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jiaze Wu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wu, J., Li, C., Huang, S. et al. Fast and robust extraction of surrogate respiratory signal from intra-operative liver ultrasound images. Int J CARS 8, 1027–1035 (2013). https://doi.org/10.1007/s11548-013-0902-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11548-013-0902-y

Keywords

Navigation