Summary
This paper presents recent work in computational modelling of diffusing gaseous neuromodulators in biological nervous systems. A variety of interesting and significant properties of such four dimensional neural signalling systems are demonstrated. It is shown that the morphology of the neuromodulator source plays a highly significant role in the diffusion patterns observed. The paper goes on to describe work in adaptive autonomous systems directly inspired by this: an exploration of the use of virtual diffusing modulators in robot nervous systems built from non-standard artificial neural networks. These virtual chemicals act over space and time modulating a variety of node and connection properties in the networks. A wide variety of rich dynamics are possible in such systems; in the work described here, evolutionary robotics techniques have been used to harness the dynamics to produce autonomous behaviour in mobile robots. Detailed comparative analyses of evolutionary searches, and search spaces, for robot controllers with and without the virtual gases are introduced. The virtual diffusing modulators are found to provide significant advantages.
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Akgoren, N. and Dalgaards, P. and Lauritzen, M. (1996). Cerebral blood flow increases evoked by electrical stimulation of rat cerebellar cortex: relation to excitatory synaptic activity and nitric oxide synthesis. Brain Res. 710, 204–214.
Bredt, D. S. and Snyder, S. H. (1990). Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci USA 87: 682–685.
Brooks, R. A. (1994). Coherent Behavior from Many Adaptive Processes. In: D. Cliff and P. Husbands and J.-A. Meyer and S. W. Wilson (Eds.), From Animals to Animats 3: Proceedings of The Third International Conference on Simulation of Adaptive Behavior, 22–29, MIT Press/Bradford Books, Cambridge, MA.
Brooks, R. A. (1991). Intelligence without representation. Artificial intelligence, 47, 139–159.
Cao, L., Blute, T. A. and Eldred, W. D. (2000). Localization of heme oxygenase-2 and modulation of cGMP levels by carbon monoxide and/or nitric oxide. Visual Neuroscience, 17: 319–379.
Cavalli-Sforza, L. and Feldman, M. (1976). Evolution of continuous variation: Direct approaches through joint distribution of genotypes and phenotypes. Proc. Nat. Academy of Sciences, USA, 73:1689–1692.
Collins, R. and Jefferson, D. (1991). Selection in massively parallel genetic algorithms. In: R. K. Belew and L. B. Booker (Eds), Proceedings of the Fourth Intl. Conf. on Genetic Algorithms, ICGA-91, 249–256, Morgan Kaufmann.
Dellaert, F. and Beer, R. D. (1996). A developmental model for the evolution of complete autonomous agents. In Pattie Maes, Maja Mataric, Jean-Arcady Meyer, Jordan Pollack, and Stewart W. Wilson(Eds.) From Animals to Animats 4: Proceedings of the Fourth International Conference on Simulation of Adaptive Behavior, Cambridge, MA: The MIT Press/Bradford Books.
Eggenberger, P. (1997). Evolving morphologies of 3D organisms based on differential gene expression. In Proc. Fourth European Conference on Artificial Life, Phil Husbands and Inman Harvey (editors), MIT Press.
Gally J. A., Montague P. R., Reeke, Jnr., G. N. and Edelman, G. M. (1990). The NO hypothesis: possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous system. Proc Natl Acad Sci USA, 87: 3547–3551.
Garthwaite, J., Charles, S. L. and Chess-Williams, R. (1988). Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intracellular messenger in the brain. Nature 336: 385–388.
Grand, S. Creatures: An exercise in Creation, IEEE Intelligent Systems magazine, July/August 1997.
Hall, Z. W. (1992). An Introduction to Molecular Neurobiology. Sinauer Associates Inc, Sunderland, Massachusetts.
Hartell, N. A. (1996). Strong activation of parallel fibres produces localized calcium transients and a form of LTD that spreads to distant synapses. Neurons 16: 601–610.
Harvey, I. and Husbands, P. and Cliff, D. (1994). Seeing the light: artificial evolution, real vision. In D. Cliff et al. (Eds.) Proc. Animals to Animats 3, MIT Press, 392–401.
Holscher, C. (1997). Nitric oxide, the enigmatic neuronal messenger: its role in synaptic plasticity. Trends Neurosci. 20: 298–303.
Husbands, P. (1998). Evolving Robot Behaviours with Diffusing Gas Networks, In: P. Husbands and J.-A. Meyer (1998), 71–86.
Husbands, P. and Meyer, J.-A. (Eds) (1998). EvoRobot98: Proceedings of 1st European Workshop on Evolutionary Robotics, Springer-Verlag LNCS 1468.
Husbands, P. and Smith, T. and Jakobi, N. and O’Shea, M. Better Living through Chemistry: Evolving GasNets for Robot Control, Connection Science, 10(3 & 4), 185–210, 1998.
Jakobi, N. (1998). Evolutionary Robotics and the Radical Envelope of Noise Hypothesis, Adaptive Behavior, 6(2): 325–368.
Kandel, E. (1976). The cellular basis of behavior. Freeman.
Katz, B. (1969). The release of neural transmitter substances. Liverpool University Press.
Kondo, T., Ishiguro, A., Uchikawa, Y. and Eggenberger, P. (1999). Autonomous Robot Control by a Neural Network with Dynamically-Rearranging Function. In: Proc. of the 4th International Symposium on Artificial Life and Robotics (AROB99), Vol. 1, pp. 324–329.
Lipson, H. and Pollack, J. B. (2000). Automatic design and manufacture of robotic life-forms, Nature 406, pp. 974–978.
Nolfi, S. and Floreano, D. (2000). Evolutionary Robotics: The biology, intelligence and technology of self-organizing machines. MIT Press.
Park, J.-H., Straub, V. and O’Shea, M. (1998). Anterograde signaling by Nitric Oxide: characterization and in vitro reconstitution of an identified nitrergic synapse. J Neurosci 18.
Philippedes, A. and Husbands, P. and O’Shea, M. Four Dimensional Neuronal Signaling by Nitric Oxide: A Computational Analysis. Journal of Neuroscience 20(3): 1199–1207, 2000.
Philippedes, A. and Husbands, P. and Lovick, T. and O’Shea, M. (2001). Targeted gas clouds in the brain. (submitted)
Smith, T. and Husbands, P. and O’Shea, M. (2001). Neutral Networks and Evovability with Complex genotype-Phenotype Mapping. Proc. ECAL’01. LNCS, Springer.
Smith, T. and Husbands, P. and O’Shea, M. (2001). Not Measuring Evovability: Initial Investigations of an Evolutionary Robotics Search Space. In Proc. CEC’01, IEEE Press.
Smith, T. and Husbands, P. and O’Shea, M. (2001). Evolvability, Neutrality and Search Difficulty. (submitted)
Wagner, G. and Altenberg, L. (1996). Complex adaptations and the evolution of evolvability. Evolution, 50(3): 967–976.
Wood, J. and Garthwaite, J. (1994) Model of the diffusional spread of nitric oxide - implications for neural nitric oxide signaling and its pharmacological properties. Neuropharmacology 33: 1235–1244.
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Husbands, P., Philippides, A., Smith, T. et al. Volume signalling in real and robot nervous systems. Theory Biosci. 120, 253–269 (2001). https://doi.org/10.1007/s12064-001-0022-z
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DOI: https://doi.org/10.1007/s12064-001-0022-z