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Varying combination of feature extraction and modified support vector machines based prediction of myocardial infarction

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Abstract

Today’s food habits, way of life causes a number of health disorders in human especially those related to heart diseases. Cardiac arrest is one such disease, which is the deadliest form is Myocardial Infarction (MI). Earlier prediction of MI would save the viability of human. This study presents a new approach in analyzing the history of patients related to heart disorders. A new feature selection and feature ranking approach is proposed to filter the high preferential features that help in early detection of MI. As the contribution capacity of different features varies in proportion, a varying combination of feature (VCF) algorithm is proposed and probabilistic principal component analysis (PPCA) is implemented to improve the feature extraction. The projected feature vectors are analyzed with respect to their covariance and the vectors with highest covariance is identified by PPCA. Thus, the VCF and PPCA reduces the dimensionality of the dataset overcoming the curse of dimensionality issue. The selected prominent features are subjected to multi-linear regression (MLR) and those combinations that are tightly related are identified. Further they are passed through radial basis function (RBF) based support vector machines (SVM) for classification. The two classes generated by SVM includes patients with and without MI. The clinical tests of patients are taken as dataset for analysis and the performance of the system is measured. The predicted patients and the mortality rate are correlated to measure the system performance. The combination of these machine learning algorithms with the chosen manifestations identifies the myocardial forecasts. The results demonstrates that the planned framework fits for predicting the MIs.

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Correspondence to A. Razia Sulthana.

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Appendix

Appendix

Variables

Description

Variables

Description

AGE

Age in years

LVEF (%)

Left ventricular ejection fraction

(LVEF: ≥ 55%) High mortality

(LVEF: < 55%)Low mortality

SEX

Male-M

TC

Total cholesterol

Female-F

 

Normal Range > 160 mg/dL

Abnormal Range > or = 200 mg/dL

Ht(m)

Hyper tension levels

HDL

High density lipoprotein

Normal range = 1.2–1.5

 

 < 40 mg/dL may be an effective warning sign for atherosclerotic development

Abnormal range > 1.5

 

 > 40 less chances or mortality

Wt(kg)

Weight in kilograms

VLDL5

Very low-density lipoprotein

Range = 25 to 50 are associated with increased coronary heart disease

BMI

Body Mass Index

LDL

Low density lipoprotein

Both male and female

 

Young adults experiencing acute MIs typically have acceptable cholesterol levels (i.e., < or = 130 mg/dL) or optimal values (ie, < or = 100 mg/dL)

Normal BMI -18.5–24.9

Abnormal range < 18.5 and > 24.9

HEART RATE

Range

TGL

Triglyceride

Normal < 80 beats per minute

 

High Serum Triglyceride Concentration Is a Cause Of The Incidence Of MI

Abnormal > 80 beats per minute

SBP

Systolic blood pressure

UREA

 > or = 25 mg/dL -High Mortality rate

Normal range 130–139

DBP

Diastolic blood pressure

CREAT

Creatinine

Normal range 85–89

 

“(Elevated group, serum creatinine > or = 1.3 mg/dl), and 2) normal serum creatinine group (normal group, serum creatinine < 1.3 mg/dl)”

DM FOR SPSS

Diabetes mellitus history

HB

Haemoglobin levels

Yes = 1

 

“The mortality was 21.6% in patients with haemoglobin levels on admission < or = 10 g/dl and 9.3% in patients with haemoglobin levels > 10 g/dl (p < 0.001).”

No = 2

HT FPR SPSS

Hyper tension

Total count

White blood cells

Yes = 1

“Median WBC peak was 11 395/mm3 (range 3100–26,900); median neutrophils peak was 8345/mm3 (range 3770–22,600), median monocytes peak was 890/mm3 (range 280–2400), and median lymphocytes peak was 2400/mm3 (range 300–12,730)”

No = 2

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Sulthana, A.R., Jaithunbi, A.K. Varying combination of feature extraction and modified support vector machines based prediction of myocardial infarction. Evolving Systems 13, 777–794 (2022). https://doi.org/10.1007/s12530-021-09410-4

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