Collective intelligence in medical diagnosis systems: A case study

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Abstract

Diagnosing a patient's condition is one of the most important and challenging tasks in medicine. We present a study of the application of collective intelligence in medical diagnosis by applying consensus methods. We compared the accuracy obtained with this method against the diagnostics accuracy reached through the knowledge of a single expert. We used the ontological structures of ten diseases. Two knowledge bases were created by placing five diseases into each knowledge base. We conducted two experiments, one with an empty knowledge base and the other with a populated knowledge base. For both experiments, five experts added and/or eliminated signs/symptoms and diagnostic tests for each disease. After this process, the individual knowledge bases were built based on the output of the consensus methods. In order to perform the evaluation, we compared the number of items for each disease in the agreed knowledge bases against the number of items in the GS (Gold Standard). We identified that, while the number of items in each knowledge base is higher, the consensus level is lower. In all cases, the lowest level of agreement (20%) exceeded the number of signs that are in the GS. In addition, when all experts agreed, the number of items decreased. The use of collective intelligence can be used to increase the consensus of physicians. This is because, by using consensus, physicians can gather more information and knowledge than when obtaining information and knowledge from knowledge bases fed or populated from the knowledge found in the literature, and, at the same time, they can keep updated and collaborate dynamically.

Introduction

In medical practice, first-contact medical care is the main entrance to health services, providing continuous and comprehensive personal attention to patients. Therefore, a proper communication channel between the first and second level of medical care is needed. Physicians use interconsulting as the main element to build this communication channel [1], [2], [3]. Mainly, this practice allows them to share information to reach a consensus about a diagnosis or treatment [4]. The ability of a physician to diagnose a patient's condition depends on several factors, such as knowledge, training, experience, available resources, communication skills and, often, instinct [5], [6], [7], [8], [9]. Sharing information is the act of disseminating valuable knowledge gained with other members within an organisation. This activity of physicians in hospitals can potentially generate huge profits and is essential to succeed and survive in competitive environments [10].

This research is based on two concepts closely related to medicine and health care: consensus methods and collective intelligence. The use of consensus methods to solve problems related to health and medicine has been increasing. These methods define levels of agreement between individuals, and, if they are used properly, it is possible to create structured environments that provide the best information that allows experts to solve problems in a more conclusive manner [11]. In [12], Heylighen defines collective intelligence as the ability of a group to solve more problems than its individual members can separately. The basic idea is that a group of individuals can be smarter together than separated. In the same manner, Lévy explains that the term Collaborative Intelligence encompasses Collective Intelligence, defined as a form of universally distributed intelligence, constantly enhanced, coordinated in real time and employing effective mobilisation skills [16].

Collaborative intelligence comes from the synergy created when individuals interact with each other following simple rules. However, collective intelligence also has some limitations. One of the main problems is that an expert may incorrectly interpret the ideas of another expert due to differences in experience, knowledge or terms used. In medicine, this problem is known as overlapping [12], [13], [14], [15].

We present a case study where physicians employed consensus methods and collective intelligence in order to obtain a medical diagnosis. We compared the diagnosis accuracy that was reached by applying collective intelligence against the diagnosis accuracy reached through the knowledge of a single expert. The experiment was supported by a Diagnosis Decision Support System (DDSS). In addition, based on the information collected, we analysed the way in which medical diagnosis was influenced by the physicians’ different opinions. All this work helped us to test the hypothesis that different levels of intelligence between a group of people and its individual members exist. Additionally, we found that these intelligence levels can be measured and used to predict the performance of groups in a variety of tasks.

The rest of this paper is structured as follows. Section 2 presents the state of the art focusing on consensus methods, which are traditionally used in the medical field. In Section 3, we outline the research description and methods used. In Section 4, we show the main results obtained. Finally, in Section 5, we present our conclusions about the results and suggest future research directions and challenges.

Section snippets

State of the art

Health care providers often face the problem of trying to make decisions in situations where there is insufficient information or where there is too much or contradictory information [17]. Medical professionals apply consensus methods to solve problems related to the use of medical knowledge and technologies. The diversity of problems is vast; for example, consensus methods can be used in intraocular lens implantation, coronary artery surgery or for treatment of breast cancer [11]. The two

Research description and methods

In medicine, physicians usually look for a more accurate diagnosis by collaborating through an information exchange. However, this collaboration is often limited due to different factors, such as the distance among and the schedule of the doctors; that is, the doctors who can collaborate in a diagnosis process are not always in the same place at the same time. Given this situation, this research is two-fold. On one hand, we intended to determine how and to what degree collaborative intelligence

Experimentation

After applying the evaluation methodology, the obtained results from an actual diagnosis system allow establishing the accuracy of the system based on objective facts. This methodology generated enough information to analyse the system's behaviour for each disease in the expert's knowledge base or in the complete knowledge base. This procedure facilitated the evaluation of medical diagnostic systems by having a reliable process based on objective facts.

As part of our research, we made an

Results

After executing the consensus algorithms for the first experiment (with an empty KB), we found that QtD showed higher values at the lower levels of the signs coincidence method. This means that the experts added more new items to their knowledge bases. Further, the QlD also showed higher values, but a greater amount of equal items, at the lower levels of the signs coincidence method. Based on this situation, we can firmly state that, even when the experts added more items at the lower levels,

Conclusions and future work

The gold standard used in this work was based in the use of individual medical knowledge obtained from the literature. Based on this fact, the experiments conducted reveal that consensus methods could be used to create new knowledge bases which will result in a higher accuracy. The proposed consensus methods are based in the concept of collective intelligence: the intelligence of a set of individuals could be better than the intelligence of the smarter of these individuals. The knowledge

Conflict of interest

Conflict of interest: None declared.

The authors of this article declare that they have not any kind of conflict of interest related with the work presented.

Acknowledgements

The authors are very grateful to the National Council of Science and Technology (CONACYT) (Grant no. (52) 5553227708) and the Public Education Secretary (SEP) through PRODEP (Grant no. (52)5536011000) for funding this research.

Gandhi Samuel Hernandez-Chan is a Computer System Engineer by the Instituto Tecnológico de Mérida, holds a Computer System Master by the same institute and has a PhD in Computer Science by the Universidad Carlos III de Madrid. Teacher of Software Engineering, Programming Languages and data bases in the IT area at the Universidad Tecnológica Metropolitana in Mérida Yucatán. He has also collaborated as teacher in other Universities like Universidad del Valle de México an Instituto Tecnológico de

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    Gandhi Samuel Hernandez-Chan is a Computer System Engineer by the Instituto Tecnológico de Mérida, holds a Computer System Master by the same institute and has a PhD in Computer Science by the Universidad Carlos III de Madrid. Teacher of Software Engineering, Programming Languages and data bases in the IT area at the Universidad Tecnológica Metropolitana in Mérida Yucatán. He has also collaborated as teacher in other Universities like Universidad del Valle de México an Instituto Tecnológico de Mérida. His research interest areas are Social Networks, Medical Portals, Ontologies, Semantic Web, Web Services, Clinical Decision Support Systems, Collaborative Intelligence and Education Applications.

    Edgar Eduardo Ceh-Varela is a Computer Systems Engineer by the Instituto Tecnologico de Merida, he has a Master degree in Information and Communication Technologies and holds a PhD in Computer Systems for the Universidad del Sur. Currently he is an Engineering teacher at Universidad Tecnológica Metropolitana in Mérida Yucatán. His research interest areas are Machine Learning, Computer Vision, and Computer Networks.

    José Luis Sánchez-Cervantes is a Computer System Engineer by the Instituto Tecnológico de Orizaba, he obtained his master degree in Computer Systems with Software Engineering specialty, and holds a PhD in Computer Science by the Universidad Carlos III de Madrid. His research interests include Semantic Web, Linked Data (Linked Open Data), Cloud Computing, Collective Intelligence and distributed systems.

    Marisol Villanueva-Escalante is a Computer System Engineer by the Instituto Tecnológico de Mérida. She obtained a master degree in Information Technologies Management by Latino University and holds a PhD in Education by Santander University. Her research interests include Informatics Applications focus on Education, Semantic Technologies, Data Mining and Data Warehouse.

    Alejandro Rodríguez-González has a degree in Computer Science, an M.Sc in Computer Science and technology in the specialty of Artificial Intelligence, an M.Sc in Engineering Decision Systems and a Phd in Computer Science by the University of Murcia, Spain. He is working as researcher in Computer Science for the Department of Engineering at the Universidad Internacional de La Rioja, and is involved in several projects of the Spanish ministry of industry. His main research interests are Semantic Web, Artificial Intelligence and the build of medical diagnosis systems using these techniques.

    Yuliana Perez-Gallardo is a PhD student in Computer Science and Technology at the University Carlos III of Madrid (Spain), she holds a bachelor and a master's degree in Computer Systems Engineering specializing in Software at Institute Technologic of Orizaba(Mexico). She has published on diverse scientific international publications via books, journals, conferences. Her current research interests include object recognition in 2D and 3D images and, recently, Semantic Technologies.

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