Mapping track density changes in nigrostriatal and extranigral pathways in Parkinson's disease☆
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Abbreviations
18F-DOPA
[18F]-l-dihydroxyphenylalanine
APM
average pathlength map
BA
Brodmann area
DA
dopamine
DTI
diffusion tensor imaging
DW
diffusion-weighted
DWI
diffusion-weighted imaging
FA
fractional anisotropy
FDG
18Fluorodeoxyglucose
FLASH
fast low-angle shot
FOD
fiber orientation distribution
IFO
inferior fronto-occipital fasciculus
ILF
inferior longitudinal fasciculus
LC
locus coeruleus
LEDD
levodopa equivalent daily dose
MD
mean diffusivity
MT
magnetization transfer
NSP
nigrostriatal pathway
PD
proton density
PDQ
Parkinson's disease questionnaire
PET
positron emission tomography
SCP
superior cerebellar peduncle
SLF
superior longitudinal fasciculus
SN
substantia nigra
TDI
track density imaging
TPM
total pathlength map
UPDRS
Unified Parkinson's Disease Rating Scale
VTA
ventral tegmental area
Keywords
Parkinson's disease
Tractography
Diffusion
White matter
Substantia nigra
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- ☆
Data for this article are available at: http://www.nitrc.org/projects/parktdi/.
- 1
These authors contributed equally to this work.
Copyright © 2014 Elsevier Inc.