Elsevier

NeuroImage

Volume 197, 15 August 2019, Pages 650-651
NeuroImage

Temporal ICA has not properly separated global fMRI signals: A comment on Glasser et al. (2018)

https://doi.org/10.1016/j.neuroimage.2018.12.051Get rights and content

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Conflicts of interest

The authors declare no conflicts of interest with respect to this report.

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    This is likely for two reasons. Firstly, even though physiologically-derived confounds have the advantage that they have a much greater a priori validity if one is concerned about mistakenly removing neural signal, there is a cost: they require extra data to be collected, inspected, and analysed (Glasser et al., 2018; 2019; Power, 2019; Power et al., 2020). Secondly, as Power et al. (2020) recently demonstrated, these fMRI artefacts typically arise in the context of unusual breathing events—very deep breaths, apnoeas, etc.—that are by definition hard for algorithms designed with “normal” tidal breathing in mind to properly detect and characterise.

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