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Strategies of European SMEs in Biotechnology: The Role of Size, Technology and Market

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Abstract

Both the technological and market focus of 228 European biotechnology SMEs are analysed in this paper. Data from the Genetic Engineering catalogue provide a complementary representation compared to the patent publications that are most commonly used. Results of the analysis produce a new view of the development of biotech SMEs. First, no pattern of specialisation by country is observed, even though three types of company with different technological focus can be distinguished in the sample. Second, it is argued that the rapid technological evolution in this domain can hardly be explained by a rapid evolution of the technological basis of the companies, and should consequently be explained primarily by the creation of new SMEs. Third, four different patterns of linkage between technology and market focus are observed, by means of co-word analysis.

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References

  • Abernathy, W., Utterback, J. M. (1978). Patterns of innovation in technology, Technology Review, 80(7): 40-47.

    Google Scholar 

  • Acs, Z.-J., Audretsch, D.-B. (1988), Innovation in large and small firms: an empirical analysis, American Economic Review, 78(4): 678-690.

    Google Scholar 

  • Anderson, P., Tushman, M. L. (1990), Technological discontinuities and dominant designs: a cyclical model of technological change, Administrative Science Quarterly, 35(4): 604-633.

    Google Scholar 

  • Callon, M., Courtial, J.-P., Turner, W. (1991), La méthode Leximappe: un outil pour l'analyse stratègique du développement scientifique et technique, In: Gestion de la recherche, nouveaux problèmes, nouveaux outils, pp. 208-251, Dominique Vinck, (Ed.), De Boeck University.

  • De Looze, M.-A, Coronini, R., Joly P.-B. (1999), A note on recent trends in knowledge creation and appropriation through genomics: a scientometric analysis, International Journal of Biotechnology, 1(2).

  • De Looze, M.-A., Ramani, S. (1999), What's the difference between the French, the British, and the Germans?: A look at biotechnology patent applications, Nature Biotechnology, January, 83-85.

  • De Looze, M.-A., Estades, J., Joly, P.-B., Ramani, S., Saviotti, P. (1996), The Role of SMEs in Technology Creation and Diffusion: Implication for European Competitiveness in Biotechnology, Report for the European Commission, CT 942032, 86 p.

  • De Looze, M.-A., Estades, J., Joly, P. B., Ramani, S., Saviotti, P. P. (1998), The Creation of European Dedicated Biotechnology Firms, In: Senker, J. (Ed.); Van Vliet, R. (Coord.) Biotechnology and Competitive Advantage: Europe's Firms and the US Challenge, Cheltenham (USA): E. Elgar, pp. 68-88.

    Google Scholar 

  • Ernst & Young (1998), European Biotech 97. A New Economy, Ernst Young International.

  • Genetic Engineering News (1998), Guides to Biotechnology Companies. Larchmont, NY, Mary Ann Liebert Inc.

  • Joly, P. B., De Looze, M.-A., Mangematin, V., Coronini, R. (1996), Genome patents, Nature, 384, 19/26, 608.

    Google Scholar 

  • Joly, P. B., De Looze, M.-A. (1998), An analysis of innovation strategies and industrial differentiation through patent applications: The case of plant biotechnology, Research Policy, (25) 1027-1046.

  • Levin, R. C., Klevorick, A. K., Nelson, R. R., Winter, S. G. (1987), Appropriating the returns from industrial research and development. Brookings Papers on Economic Activity, (3) 783-820.

  • Malerba, F., Orsenigo, L. (1996), Schumpeterian patterns of innovation are technology specific, Research Policy, 25(3): 451-478.

    Google Scholar 

  • McCain, K. W. (1995), The structure of biotechnology R&D, Scientometrics, 32,(2) 153-175.

    Google Scholar 

  • Niosi, J. (1999), National Systems of Innovation are “x-efficient” (and “x-effective”). Why Some Are Slow Learners?, A presentation to the DRUID Conference on National Systems of Innovation, June.

  • Orsenigo, L. (1989), The Emergence of Biotechnology: Institutions and Markets in Industrial Innovation, New York, St. Martin's Press, 230.

    Google Scholar 

  • Powell, W. W., Koput, K. W., Smith-Doerr, L. (1996), Inter-organisational collaboration and the locus of innovation: Networks of learning in biotechnology, Administrative Science Quaterly, 41: 116-145.

    Google Scholar 

  • Saviotti, P. P. (1998), Industrial structure and the dynamics of knowledge generation in biotechnology. In: J. Senker and R. Van Vliet (Eds) Biotechnology and Competitive Advantage: Europe's Firms and US Advantage. Cheltenhamm (USA), E. Elgar, pp. 19-43.

    Google Scholar 

  • Saviotti, P. P., Joly, P.-B., Estades, J., Ramani, S., de Looze, M.-A. (1998), The creation of European dedicated biotechnology firms. In: J. Senker and R. Van Vliet, (Eds) Biotechnology and Competitive Advantage: Europe's Firms and US Advantage. Cheltenhamm (USA), E. Elgar, pp. 66-88.

    Google Scholar 

  • Senker, J., Sharp, M. (1997), Organizational learning in cooperative alliances: some case studies in biotechnology, Technology Analysis and Strategic Management, 9(1): 35-51.

    Google Scholar 

  • Sharp, M., (1995), The science of nations: European multinationals and American biotechnology, International Journal of Technology Management, (Biotechnology Review).

  • Walsh, V., Galimberti, I. (1993), Firm strategies, globalisation and new technological paradigms: The case of biotechnology, Humbert, Marc, (Ed.) The Impact of Globalisation on Europe's Firms and Industries. London, Pinter, pp. 175-190.

    Google Scholar 

  • Walsh, V., Niosi, J., Mustar, P. (1995), Small-firm formation in biotechnology: A comparison of France, Britain and Canada, Technovation 15(5): 303-327.

    Google Scholar 

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Lemarié, S., de Looze, MA. & Mangematin, V. Strategies of European SMEs in Biotechnology: The Role of Size, Technology and Market. Scientometrics 47, 541–560 (2000). https://doi.org/10.1023/A:1005624017982

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