The development of photonic integrated circuits (PICs) has made it possible to accomplish on-chip optical interconnects and computations. As a promising alternative to traditional CMOS circuits, optics has demonstrated the ability to realize ultra-high speed and low-power information processing and communications. In this work, we propose a logic synthesis methodology for PICs. For the first time, practical issues including the insertion losses from optical combiners and switches are considered. Two optimization techniques based on binary decision diagram, combiner elimination and coupler assignment, are proposed to improve the power efficiency for PICs. Experimental results of MCNC and IWLS combinational benchmarks showed our method could efficiently generate quality PICs with a 27.02X better optical power efficiency on average, and greatly reduce the optical power depletion and facilitate large-scale on-chip optical computation.