Differentially expressed genes selection via Truncated Nuclear Norm Regularization | IEEE Conference Publication | IEEE Xplore

Differentially expressed genes selection via Truncated Nuclear Norm Regularization


Abstract:

Robust Principal Component Analysis (RPCA) is an efficient method in the selection of differentially expressed genes. However, nuclear norm minimizes all singular values ...Show More

Abstract:

Robust Principal Component Analysis (RPCA) is an efficient method in the selection of differentially expressed genes. However, nuclear norm minimizes all singular values simultaneously, so it may not be the best solution to replace the low-rank function. In this paper, the truncated nuclear norm is introduced. And a new method named Truncated nuclear norm regularized Robust Principal Component Analysis (TRPCA) is proposed. The method decomposes the observation matrix of genomic data into a low-rank matrix and a sparse matrix. The differentially expressed genes can be selected according to the sparse matrix. The experimental results on the The Cancer Genome Atlas (TCGA) data illustrate that the TRPCA method outperforms other state-of-the-art methods in the selection of differentially expressed genes.
Date of Conference: 15-18 December 2016
Date Added to IEEE Xplore: 19 January 2017
ISBN Information:
Conference Location: Shenzhen

References

References is not available for this document.