Abstract:
Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functio...Show MoreMetadata
Abstract:
Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functional variants responsible for severe asthma in Korean population. We identified 10 variants of 6 candidate asthma genes (P <; 10-5) comprising GPR88, AGTRAP, GTP2IRD1, KANK1, DNHD1 and DCUN1D2. Our study provides possible new therapeutic targets for asthma.
Date of Conference: 03-06 December 2018
Date Added to IEEE Xplore: 24 January 2019
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