In this paper we propose an image matching approach that selects the method of matching for each region in the image based on the region properties. This method can be used to find images similar to a query image from a database, which is useful for automatic image and video annotation. In this approach, each image is first divided into large homogeneous areas, identified as “texture areas”, and non-texture areas. Local descriptors are then used to match the keypoints in the non-texture areas, while texture regions are matched based on low level visual features. Experimental results prove that while exclusion of texture areas from local descriptor matching increases the efficiency of the whole process, utilization of appropriate measures for different regions can also increase the overall performance.