Power conservation has been an important area of interest in Wireless Sensor Network (WSN). Medium Access Control (MAC) protocols play an important factor in power consumption. As wireless sensors operate on batteries, periodically replacement of which is considered a critical issue. So that a different scenario has been designed and implemented to optimize the power consumption with life operating increases for these sensors through a different efficient protocol across layers. However, there are four main classes of MAC protocols due to how the node organizes within the shared radio channel. This work studies and compares the typical protocols (S-MAC, T-MAC, BMAC, L-MAC, and Crankshaft), which cover the four classes, analyzes their performances, and then evaluate the results. The purposes of this experiment are to know how these protocols interact with typical network conditions and how power consumption can be monitored to determine the optimal protocol for each application.