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The effect of multiplicity of infection on the temperateness of a bacteriophage: Implications for viral fitness | IEEE Conference Publication | IEEE Xplore

The effect of multiplicity of infection on the temperateness of a bacteriophage: Implications for viral fitness


Abstract:

Since phage-bacteria interactions are among the most abundant in nature, they have become in the object of intensive study. In particular, how phages evolved temperatenes...Show More

Abstract:

Since phage-bacteria interactions are among the most abundant in nature, they have become in the object of intensive study. In particular, how phages evolved temperateness - the propensity of the phage to enter lysogeny - and how temparateness has been optimized, remains poorly understood. In this work, we study the advantages of the lysogeny over the lytic path in phages under fluctuating environments. Also we explore how multiplicity of infection (MOI) drives the decision made by the phage. We found that temperate phages might use the lysogenic path to protect themselves from long periods of bad conditions. Additionally, phages with MOI strategies might have better chances of survive long periods of detrimental conditions.
Date of Conference: 12-15 December 2017
Date Added to IEEE Xplore: 22 January 2018
ISBN Information:
Conference Location: Melbourne, VIC, Australia

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