Aiming at the problem of poor real-time calculation of air-to-air missile impact area, a method for fast calculation of air-to-air missile impact area based on improved least squares method is proposed. Firstly, the original data is simulated by the dichotomy-based proportional navigation method, and then the improved least squares method is used to fit the impact area, and finally the simulation results are compared with the real results. It can be seen from the simulation results that when the algorithm solves the problem of the air-to-air missile impact area, the calculation accuracy satisfies the error requirement, and the calculation speed satisfies the real-time requirement. The conclusion is that when the improved least squares algorithm solves the real-time calculation of the air-to-air missile impact area, the algorithm has certain engineering significance.