Nowadays, agile manufacturing has aroused great attention all over the world. With the competition of the markets getting much more severe, it is becoming imperative to construct a highly efficient agile manufacturing system conforming to customer requirement in products' R&D, manufacture, sales and service. Besides manufacturing management, data deeply utilization, e-commerce and production optimization is also necessary for manufacturing enterprise. This paper analyzes the main feature of customer-driven manufacturing system and points out that there are four crucial subsystems, namely integrated manufacturing subsystem, data warehouse subsystem, quick responding subsystem and e-sales subsystem, catering to the requirements of various customers in time. The production of iron & steel enterprises is a long-term manufacture mode mixed with chemical process and physical process. The processing mode of iron and steel manufacturing has its own unique style. This also paper provides the realization case of customer-driven agile manufacturing system in Baosteel.