This work proposes a wafer probe parametric test set optimization method for predicting dies which are likely to fail in the field based on known in-field or final test fails. Large volumes of wafer probe data across 5 lots and hundreds of parametric measurements are optimized to find test sets that help predict actually observed test escapes and final test failures. Simple rules are generated to explain how test limits can be tightened in wafer probe to prevent test escapes and final test fails with minimal overkill. The proposed method is evaluated on wafer probe data from a current automotive IC with near zero DPPM requirements resulting in improved test quality and reduced test cost.