This paper describes a practical method for sidelobe suppression for orthogonal frequency-division multiplexing (OFDM) signals. Most of the existing sidelobe suppression techniques are computationally expensive. The proposed technique is simpler in terms of computational complexity, and it enables high suppression capability. In addition, most of the related work deals with either sidelobe suppression or peak-to-average power ratio (PAPR) reduction which are mutually exclusive in some cases. However, the proposed technique is compatible with some PAPR reduction techniques. Simulation results show that the proposed technique can achieve significant sidelobe suppression. In addition, under adjacent channel interference constraints, the proposed algorithm outperforms the conventional OFDM transmissions in terms of bit-error rate (BER). Moreover, the proposed algorithm is implemented on a software defined radio and tested for practical and real-time transmissions.