The development of World Wide Web (WWW) a little more than a decade ago has caused an information explosion that needs an Intelligent Web (IW) for users to easily control their information and commercial needs. Therefore, engineering schools have offered a variety of IW courses to cultivate hands-on experience and training for industrial systems. In this study, Intelligent Teaching Models for STEM Related Careers Using Service-Oriented Architecture (SOA) and Management Science project course has been designed. The goal is to help students learn theoretical concepts of IW, practice advanced technical skills, and discover knowledge to solve problem. Undergraduate Science, Technology, Engineering and Mathematics (STEM) students involved in the development of innovative approaches and techniques. They are able to help solve the problems of disease misdiagnoses that medical and health care professionals experience. They co-authored and presented numerous research papers introducing the solution via scientific conferences and journals. This study provides the solution in the form of an Intelligent models using an integration of Service-Oriented Architecture and Management Science to decrease disease misdiagnosis in health care. Results show that this new course strengthens the capacity and quality of STEM undergraduate degree programs and the number of overall graduate student enrollment. It promotes a vigorous STEM academic environment and increases the number of students entering STEM careers. It expands the breadth of faculty and student involvement in research and development. It enhances and leverages the active engagement of faculty technology transfer and translational research. It improves and develops new relationships between educational institutions and research funding entities to broaden the university's research portfolio and increase funding. The proposed project course is a software engineering research methodology, an educational tool, and a teaching tech...