Abstract:
Imaging artifacts in Transrectal Ultrasound (TRUS) images and inter-patient variations in prostate shape and size challenge computer-aided automatic or semi-automatic seg...Show MoreMetadata
Abstract:
Imaging artifacts in Transrectal Ultrasound (TRUS) images and inter-patient variations in prostate shape and size challenge computer-aided automatic or semi-automatic segmentation of the prostate. In this paper, we propose to use multiple mean parametric models derived from principal component analysis (PCA) of shape and posterior probability information to segment the prostate. In contrast to traditional statistical models of shape and intensity priors, we use posterior probability of the prostate region determined from random forest classification to build, initialize and propagate our model. Multiple mean models derived from spectral clustering of combined shape and appearance parameters ensure improvement in segmentation accuracies. The proposed method achieves mean Dice similarity coefficient (DSC) value of 0.96±0.01, with a mean segmentation time of 0.67±0.02 seconds when validated with 46 images from 23 datasets in a leave-one-patient-out validation framework.
Published in: 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Date of Conference: 28 August 2012 - 01 September 2012
Date Added to IEEE Xplore: 10 November 2012
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PubMed ID: 23366392