This paper presents and analyzes the factors that have arisen on the implementation of the medical technology assessment and management courses, and the academic methodologies used to deal with them. Five courses that cover topics as Technology Management, Health Economics, Quality Assessment, Innovation and Entrepreneurship were designed as electives for BME curriculum and have been taught for the last two years. The activities carried out within the courses are described and their impact on the comprehension of the course contents are presented. Also, several elements and factors pertaining to the teaching-learning process are discussed. Future perspectives for the students that follow this sub-specialty branch of the BME curriculum are presented