The studies on seizure prediction problem have shown great improvement these years. Machine learning based seizure prediction method shows great performance by doing pattern recognition on high-dimensional bivariate synchronization features. However, the computation loading of the machine learning based method may be too high to meet wearable or implantable devices with the power and area constraints. In this work, channel selection is proposed to reduce the channel number from 22 to less than 6 channels and therefore more than 93.73% of the computation loading is saved through the method. The best result shows successful rate of 60.6% in 3-channel cases of ECoG database and successful rate of 70% in 3-channel cases of EEG database.